{"id":"W2166894188","doi":"10.1016/j.ajhg.2015.09.005","title":"Imputation of KIR Types from SNP Variation Data","year":2015,"lang":"en","type":"article","venue":"The American Journal of Human Genetics","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University and Génome Québec Innovation Centre","funders":"Cambridge Institute for Medical Research, University of Cambridge; Wellcome Trust","keywords":"Human leukocyte antigen; Imputation (statistics); Biology; SNP; Population; Genetics; Genome-wide association study; Immunology; Computational biology; Typing; Single-nucleotide polymorphism; Gene; Antigen; Genotype; Medicine; Missing data; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003384686,0.00005729441,0.0001624156,0.00005753085,0.00004817551,0.000008481915,0.0003099302,0.00002429671,0.0001430482],"category_scores_gemma":[0.00006407167,0.00003958494,0.00003385798,0.00007167186,0.0001445997,0.0000739177,0.00005855937,0.0001499502,0.00004950349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002142028,"about_ca_system_score_gemma":0.0000567125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001441501,"about_ca_topic_score_gemma":0.000005519673,"domain_scores_codex":[0.9992896,0.000212766,0.0003180855,0.00006392597,0.0000472895,0.00006833893],"domain_scores_gemma":[0.9986471,0.00007345839,0.0007755588,0.0002700664,0.0002217541,0.00001207988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006494473,0.0001344498,0.001620706,0.000002467559,0.0005085333,0.000001187718,0.004096548,0.0006527168,0.93643,0.0001036159,0.0237053,0.03209503],"study_design_scores_gemma":[0.008467274,0.01731105,0.3317485,0.000191156,0.002111458,0.0006537548,0.02547859,0.001788022,0.4273404,0.01000481,0.1740236,0.000881412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940439,0.001407395,0.002864969,0.0001799396,0.001220027,0.00003437499,0.000006795984,0.000004765079,0.000237841],"genre_scores_gemma":[0.9990071,0.00007849233,0.0003598194,0.0001066539,0.0001019075,2.005794e-7,0.00006548675,0.000006661279,0.0002736568],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5090896,"threshold_uncertainty_score":0.1614227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0508731411487762,"score_gpt":0.3051186871401952,"score_spread":0.254245545991419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}