{"id":"W2166933033","doi":"10.1101/cshperspect.a016915","title":"Presynaptic Membrane Retrieval and Endosome Biology: Defining Molecularly Heterogeneous Synaptic Vesicles","year":2013,"lang":"en","type":"review","venue":"Cold Spring Harbor Perspectives in Biology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; School of Medicine, Emory University; National Institutes of Health; Canada Excellence Research Chairs, Government of Canada; Emory University","keywords":"Synaptic vesicle; Biology; Exocytosis; Vesicle; Kiss-and-run fusion; Endosome; Synapse; Endocytosis; Vesicle fusion; Neuroscience; Bulk endocytosis; Synaptic vesicle recycling; Cell biology; Secretion; Cell; Biochemistry; Membrane; Intracellular","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003181919,0.0006626213,0.001331207,0.000327757,0.0001035287,0.00004901666,0.0004449088,0.001139027,0.00003042684],"category_scores_gemma":[0.000206079,0.0006257179,0.0003697714,0.0002116815,0.0005092773,0.000008962517,0.000241973,0.0005358329,0.00002557236],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001188623,"about_ca_system_score_gemma":0.000165008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005629463,"about_ca_topic_score_gemma":0.00001669123,"domain_scores_codex":[0.9968516,0.0003801633,0.0006560259,0.001370187,0.00008319211,0.0006588816],"domain_scores_gemma":[0.9987319,0.00009917624,0.0002889337,0.0006527426,0.00007800996,0.0001492199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001712235,0.0002292871,0.0008227897,0.003373503,0.001635641,0.0001285849,0.0001858337,0.000008392768,0.9546585,0.02678945,0.000001923814,0.01199488],"study_design_scores_gemma":[0.002779133,0.002620352,0.0005775368,0.004049147,0.001642925,0.0001875048,0.0001801376,0.0001761325,0.01799954,0.0003977594,0.9653745,0.004015306],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05837868,0.9395908,0.0007434977,0.00001426007,0.0002261498,0.0008834701,0.00005475778,0.00004416735,0.00006417534],"genre_scores_gemma":[0.1264245,0.8723274,0.0005430494,0.00002099931,0.0001759483,0.0001289708,0.0002627259,0.00009526953,0.00002106896],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9653726,"threshold_uncertainty_score":0.9996194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02067998305215433,"score_gpt":0.2818622298726021,"score_spread":0.2611822468204478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}