{"id":"W2166935665","doi":"10.1111/jvh.12468","title":"Peginterferon add‐on results in more HBsAg decline compared to monotherapy in HBeAg‐positive chronic hepatitis B patients","year":2015,"lang":"en","type":"article","venue":"Journal of Viral Hepatitis","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"Foundation for Liver Research; Novartis; F. Hoffmann-La Roche; Abbott Fund; Roche; Merck; Gilead Sciences; Medtronic; Boehringer Ingelheim","keywords":"HBsAg; Medicine; Entecavir; Gastroenterology; PEG ratio; HBeAg; Combination therapy; Internal medicine; Discontinuation; Lamivudine; Hepatitis B virus; Peginterferon alfa-2a; Hepatitis B; Chronic hepatitis; Immunology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003632858,0.0004543001,0.001857758,0.0003568975,0.0001688157,0.0007915507,0.0002223082,0.0006233687,0.002242561],"category_scores_gemma":[0.003246985,0.000384295,0.003217795,0.0003241625,0.0003388765,0.0004375392,0.0002779488,0.0008215166,0.000237335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003920979,"about_ca_system_score_gemma":0.0005195774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004664344,"about_ca_topic_score_gemma":0.0009727459,"domain_scores_codex":[0.997722,0.001558187,0.0001999815,0.0002217345,0.0001438408,0.0001543362],"domain_scores_gemma":[0.9970803,0.001731244,0.0005840136,0.000217414,0.00009337713,0.0002936213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8413712,0.003937632,0.05929421,0.001036297,0.009666479,0.0002217305,0.0001892363,0.001042133,0.01458138,0.000111778,0.0005800786,0.06796785],"study_design_scores_gemma":[0.1492598,0.3189242,0.4993099,0.0002863882,0.01814636,0.0005871925,0.0002909524,0.00255122,0.006412017,0.0004914293,0.003658877,0.00008162385],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970992,0.002161755,0.00007028727,0.00007799288,0.00004248118,0.00006427356,0.000112389,0.000006283136,0.000365333],"genre_scores_gemma":[0.9986858,0.0004683177,0.0001091364,0.0001298085,0.00004774112,0.00005397399,0.0001427526,0.000003534174,0.0003589651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003632858,"threshold_uncertainty_score":0.0192126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03004416677783156,"score_gpt":0.3229129668625935,"score_spread":0.2928688000847619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}