{"id":"W2167096616","doi":"10.1128/jvi.02451-06","title":"Model for T-Antigen-Dependent Melting of the Simian Virus 40 Core Origin Based on Studies of the Interaction of the Beta-Hairpin with DNA","year":2007,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Polyomavirus and related diseases","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Helicase; DNA; Duplex (building); Prokaryotic DNA replication; Molecular biology; DNA replication; Origin of replication; Biophysics; Virology; RNA; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005532248,0.0001087277,0.0003985311,0.00008900274,0.00008583601,0.000001537606,0.0001959301,0.00008760823,0.000008452679],"category_scores_gemma":[0.0002391038,0.0000411631,0.0003008027,0.0001142492,0.0002599383,0.0000319386,0.00003915924,0.0003274357,1.662629e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005556005,"about_ca_system_score_gemma":0.0001962722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002658438,"about_ca_topic_score_gemma":0.0001102699,"domain_scores_codex":[0.9987918,0.00007844308,0.0005718813,0.0000827566,0.0003267153,0.00014842],"domain_scores_gemma":[0.9979935,0.0003075583,0.001171142,0.0002457227,0.0002402741,0.00004174924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02237636,0.001895666,0.1507286,0.0003645756,0.002596311,0.00002758439,0.002584766,0.116781,0.6978044,0.0006127037,0.001063683,0.003164415],"study_design_scores_gemma":[0.009938883,0.004436083,0.3264552,0.002085438,0.003005032,0.0002966092,0.002797969,0.07414559,0.5753231,0.0007810395,0.0005310566,0.0002039989],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996501,0.0005748631,0.0005093699,0.001640182,0.0003739417,0.0002603331,0.00001705297,0.000002085899,0.0001211962],"genre_scores_gemma":[0.9991112,0.00007020491,0.0001252477,0.0005231408,0.00007646656,0.000001580812,2.887651e-7,0.0000116116,0.00008021349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1757266,"threshold_uncertainty_score":0.1678583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0832351517411297,"score_gpt":0.3665703496626607,"score_spread":0.283335197921531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}