{"id":"W2167131644","doi":"10.4049/jimmunol.1401492","title":"CD28 Inhibits T Cell Adhesion by Recruiting CAPRI to the Plasma Membrane","year":2015,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"York University","keywords":"Rap1; CD28; Cell biology; Cell adhesion; Chemistry; Adhesion; Secretion; Small GTPase; Biology; Signal transduction; T cell; Cell; Biochemistry; Immunology; Immune system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009854485,0.0002784565,0.0002603043,0.0001369855,0.0001232853,0.0002062238,0.0002294645,0.0002395286,0.001061731],"category_scores_gemma":[0.0001665967,0.0001033692,0.0001831689,0.00006631445,0.0001736602,0.0001046545,0.0001824139,0.0007220646,0.000431045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002444504,"about_ca_system_score_gemma":0.0002406927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003800192,"about_ca_topic_score_gemma":0.0005926518,"domain_scores_codex":[0.9998217,0.00004169745,0.00001147401,0.00002053798,0.00004574095,0.0000589134],"domain_scores_gemma":[0.9999263,0.00001991903,0.00001280742,0.00001059883,0.000009327587,0.0000210873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001032177,0.00004688714,0.00009887385,0.00003708264,0.00000488956,0.00004405194,0.000008007778,0.00006986223,0.9975508,0.000090549,0.0001245614,0.001821251],"study_design_scores_gemma":[0.00002965555,0.0003700697,0.002296451,0.0000051943,0.000008809768,0.0002216689,0.00001159907,0.001484081,0.9929516,0.0000489917,0.002569514,0.000002442076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905326,0.003201423,0.002069652,0.0002407626,0.00004742575,0.00003471467,0.00009421183,0.00009904947,0.003680075],"genre_scores_gemma":[0.9952424,0.001039062,0.001352217,0.0001129757,0.00002408463,0.00003612829,0.000157419,0.00001114843,0.002024581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001061731,"threshold_uncertainty_score":0.003551841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02323490572880972,"score_gpt":0.2327410741254964,"score_spread":0.2095061683966866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}