{"id":"W2167143381","doi":"10.1139/y09-133","title":"Role of the cytoskeleton in Cd<sup>2+</sup>-induced death of mouse mesangial cellsThis article is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease.","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Heavy Metal Exposure and Toxicity","field":"Environmental Science","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs","funders":"Canadian Institutes of Health Research","keywords":"Cell biology; Cytoskeleton; Actin cytoskeleton; Biology; Programmed cell death; p38 mitogen-activated protein kinases; Cytochalasin D; Actin; Apoptosis; Reactive oxygen species; Protein kinase A; Kinase; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003555725,0.00007560458,0.0003194672,0.0001487879,0.00002514361,0.000001422296,0.0001163577,0.00008635729,0.002403382],"category_scores_gemma":[0.00008060906,0.00006160751,0.00003690306,0.0002145433,0.0002626715,0.00009164392,0.00002179744,0.0003455248,3.599354e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006000819,"about_ca_system_score_gemma":0.0003236585,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.01106224,"about_ca_topic_score_gemma":0.02837165,"domain_scores_codex":[0.9988762,0.0003327276,0.0004038896,0.0001214895,0.00007724926,0.0001885058],"domain_scores_gemma":[0.9993235,0.00008198714,0.0002761663,0.00005878314,0.00001843514,0.000241073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003186433,0.000163079,0.1335219,0.00003390984,0.00001515037,0.000001878215,0.001988353,0.0004873516,0.8624102,0.0000395056,0.00007554553,0.0009444123],"study_design_scores_gemma":[0.0007948044,0.0004467499,0.353924,0.00001819583,0.000008884316,0.00000149144,0.0001419927,0.0002040266,0.6438583,0.0004425836,0.0001196552,0.00003930709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989864,0.00002733167,1.069237e-7,0.0005877718,0.00007486813,0.0001417753,0.00002906253,3.347634e-7,0.00015231],"genre_scores_gemma":[0.9995992,0.00002526837,0.00002136044,0.0002497989,0.00008900263,0.000001681289,7.376004e-7,0.000003491111,0.000009515197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2204021,"threshold_uncertainty_score":0.9985086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00838633700520284,"score_gpt":0.2440687305922767,"score_spread":0.2356823935870739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}