{"id":"W2167203210","doi":"10.4049/jimmunol.174.11.6772","title":"Specific T Regulatory Cells Display Broad Suppressive Functions against Experimental Allergic Encephalomyelitis upon Activation with Cognate Antigen","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Myelin oligodendrocyte glycoprotein; Experimental autoimmune encephalomyelitis; Immunology; Autoimmunity; Myelin basic protein; Biology; FOXP3; Myelin; Proteolipid protein 1; Antigen; T cell; Transgene; Myelin proteolipid protein; IL-2 receptor; Cell biology; Immune system; Biochemistry; Gene; Neuroscience; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004097422,0.00036127,0.0005468833,0.0002699358,0.0005428838,0.00002293031,0.0006825664,0.0003923121,0.001163695],"category_scores_gemma":[0.00001795842,0.0002332856,0.0001797565,0.0002029745,0.000926918,0.0003801285,0.0001451878,0.001031349,0.0005761731],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000166515,"about_ca_system_score_gemma":0.0001474294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003731892,"about_ca_topic_score_gemma":0.00001334571,"domain_scores_codex":[0.9975607,0.0007089419,0.0007524207,0.0002698592,0.0001037624,0.0006042819],"domain_scores_gemma":[0.9980171,0.0003036002,0.0008693685,0.0005212819,0.0002532447,0.00003536792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002176887,0.0003742879,0.00006450513,0.000003132769,0.0008519673,0.00002073616,0.001744739,0.000357447,0.9850746,0.0001628398,0.004022967,0.005145879],"study_design_scores_gemma":[0.003230426,0.001108744,0.002443781,0.0000694543,0.00006807646,0.001350896,0.002654669,0.000004122135,0.8823971,0.00002223572,0.1063937,0.0002568073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9740054,0.02187199,0.0003236831,0.000910477,0.00151985,0.0002498175,0.00001581876,0.00004297452,0.001059992],"genre_scores_gemma":[0.9940415,0.002916183,0.0001051661,0.0002222179,0.000218723,0.000009941368,0.00004828681,0.00003837088,0.002399626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1026775,"threshold_uncertainty_score":0.9997494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00867877956396677,"score_gpt":0.2113375289181887,"score_spread":0.202658749354222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}