{"id":"W2167203210","doi":"10.4049/jimmunol.174.11.6772","title":"Specific T Regulatory Cells Display Broad Suppressive Functions against Experimental Allergic Encephalomyelitis upon Activation with Cognate Antigen","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Myelin oligodendrocyte glycoprotein; Experimental autoimmune encephalomyelitis; Immunology; Autoimmunity; Myelin basic protein; Biology; FOXP3; Myelin; Proteolipid protein 1; Antigen; T cell; Transgene; Myelin proteolipid protein; IL-2 receptor; Cell biology; Immune system; Biochemistry; Gene; Neuroscience; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002275247,0.0004166935,0.0003376252,0.0002239773,0.00008446746,0.0002004734,0.0001498327,0.0002700365,0.0007029836],"category_scores_gemma":[0.0001325094,0.0001065905,0.0001695509,0.0001138005,0.0001750635,0.0001349485,0.0001211192,0.0007161245,0.0002890437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007830322,"about_ca_system_score_gemma":0.0001028381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007115688,"about_ca_topic_score_gemma":0.0001991922,"domain_scores_codex":[0.9997261,0.00005166487,0.00002635876,0.00005508405,0.00006962313,0.00007113973],"domain_scores_gemma":[0.9998994,0.00002470604,0.00002543265,0.00001566761,0.000009180908,0.00002562029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001278605,0.0001078257,0.0002621962,0.0000385192,0.000003741633,0.00006517356,0.00001234285,0.00009278148,0.994864,0.0000537517,0.00002908783,0.004342646],"study_design_scores_gemma":[0.0001265727,0.00370741,0.006151682,0.00001756251,0.00006434253,0.001072631,0.00002896287,0.001061743,0.9842912,0.0001052406,0.003364133,0.000008512608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944232,0.001851851,0.002022745,0.00004650834,0.00002422105,0.00004471482,0.00009866214,0.0001146164,0.001373552],"genre_scores_gemma":[0.995001,0.001076083,0.002089254,0.0001024548,0.00004276818,0.00005058419,0.0002484144,0.00002012507,0.001369291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007029836,"threshold_uncertainty_score":0.002351701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00867877956396677,"score_gpt":0.2113375289181887,"score_spread":0.202658749354222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}