{"id":"W2167251244","doi":"10.1002/jcp.25090","title":"Distinct Roles for Intestinal Epithelial Cell‐Specific Hdac1 and Hdac2 in the Regulation of Murine Intestinal Homeostasis","year":2015,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Biology; Intestinal epithelium; Paneth cell; HDAC1; Cell biology; Histone deacetylase 2; Cancer research; Molecular biology; Epithelium; Histone; Histone deacetylase; Genetics; Endocrinology; Small intestine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002612827,0.0006669085,0.0004392718,0.0006577254,0.0001584173,0.0004679884,0.0003371472,0.0003811718,0.00108137],"category_scores_gemma":[0.000109177,0.0003750682,0.0004932151,0.0001737635,0.0003278899,0.0003074164,0.0002982711,0.0006860469,0.0004175213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003912514,"about_ca_system_score_gemma":0.0002474991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004422659,"about_ca_topic_score_gemma":0.000871974,"domain_scores_codex":[0.9997017,0.0000282007,0.00003273741,0.00008720757,0.00005905815,0.00009100485],"domain_scores_gemma":[0.9997768,0.00001379171,0.00006610754,0.00002760365,0.00001654958,0.0000991027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002548478,0.00002211707,0.0003402486,0.00002813159,0.000007213195,0.00003239013,0.00001057062,0.00003761031,0.9982309,0.0001187096,0.00001797322,0.0008993159],"study_design_scores_gemma":[0.00006966855,0.0004632505,0.01416114,0.00001549897,0.00006611591,0.0004561184,0.00004269318,0.000747658,0.981632,0.00008704259,0.002247171,0.00001169114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832652,0.007672581,0.005905827,0.000136175,0.000047498,0.00004386907,0.0007759036,0.0001371099,0.002016024],"genre_scores_gemma":[0.9894415,0.002109732,0.003879439,0.00008024646,0.00002254126,0.00006646298,0.0008413279,0.00005452345,0.003504251],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00108137,"threshold_uncertainty_score":0.003617585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02108837306789513,"score_gpt":0.2542360675785532,"score_spread":0.233147694510658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}