{"id":"W2167395503","doi":"10.1161/circresaha.113.301302","title":"Quaking, an RNA-Binding Protein, Is a Critical Regulator of Vascular Smooth Muscle Cell Phenotype","year":2013,"lang":"en","type":"article","venue":"Circulation Research","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Myocardin; Vascular smooth muscle; Biology; RNA-binding protein; Cell biology; Neointima; RNA splicing; Alternative splicing; Spliceosome; Gene knockdown; Messenger RNA; Exon; Serum response factor; Regulator; RNA; Splicing factor; Cancer research; Transcription factor; Internal medicine; Endocrinology; Gene; Genetics; Restenosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002395409,0.0003585446,0.0001943825,0.0001965504,0.0003083842,0.000260277,0.0002061766,0.00041543,0.001420757],"category_scores_gemma":[0.0002279981,0.0001242884,0.0001483027,0.0001296804,0.0004059536,0.0001792058,0.000221572,0.0003851567,0.0003276968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003453525,"about_ca_system_score_gemma":0.000213565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003738719,"about_ca_topic_score_gemma":0.0004729633,"domain_scores_codex":[0.9998251,0.00002322397,0.00001374731,0.00006234289,0.00005019664,0.00002557113],"domain_scores_gemma":[0.9997556,0.0000452214,0.0001123502,0.00001539777,0.00002610725,0.00004537087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006612714,0.000009183318,0.0003822674,0.00003705939,0.000002472373,0.00005283073,0.000006770612,0.00003862522,0.997354,0.0001717021,0.00005495314,0.001824077],"study_design_scores_gemma":[0.00003201359,0.000645932,0.02695391,0.00002361462,0.00004615561,0.0009646881,0.00004236657,0.002259589,0.9581058,0.0005332765,0.01037335,0.0000194193],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9626102,0.01195338,0.02044596,0.0006268072,0.0002244274,0.00007183782,0.0004783223,0.0004248328,0.003164295],"genre_scores_gemma":[0.9907668,0.00192752,0.003668217,0.000155459,0.00004061428,0.00003678325,0.000353693,0.00003289619,0.003018049],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001420757,"threshold_uncertainty_score":0.004752934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04176713404445048,"score_gpt":0.3515860790595684,"score_spread":0.3098189450151179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}