{"id":"W2167454178","doi":"10.1007/s12033-010-9286-1","title":"Enhanced Gene Delivery Mediated by Low Molecular Weight Chitosan/DNA Complexes: Effect of pH and Serum","year":2010,"lang":"en","type":"article","venue":"Molecular Biotechnology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":false,"has_abstract":true,"ca_institutions":"Polytechnique Montréal","funders":"Canadian Institutes of Health Research","keywords":"Transfection; Lipofectamine; Chitosan; Gene delivery; Chemistry; Flow cytometry; Cytotoxicity; Dynamic light scattering; Biophysics; DNA; Fluorescence; Molecular biology; HEK 293 cells; Biochemistry; Gene; In vitro; Biology; Nanotechnology; Materials science; Recombinant DNA; Vector (molecular biology); Nanoparticle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007326161,0.00049297,0.000475118,0.0002092062,0.0001484926,0.0005503621,0.0002885214,0.0004125277,0.0003907765],"category_scores_gemma":[0.0007975078,0.0002250066,0.0002873673,0.0001918671,0.0004205139,0.0004152509,0.0002473305,0.0003862738,0.0001643465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006159483,"about_ca_system_score_gemma":0.000474571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001176846,"about_ca_topic_score_gemma":0.00142582,"domain_scores_codex":[0.9995965,0.00009799147,0.00005046555,0.00007584032,0.0001291514,0.00004993415],"domain_scores_gemma":[0.9995745,0.0001845355,0.0001046338,0.00002328278,0.00007338059,0.00003970477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003943084,0.000009193172,0.00005748151,0.00002836754,0.000002758112,0.0000171547,0.00001119668,0.00005322582,0.9993254,0.00002032046,0.000004918367,0.0004306098],"study_design_scores_gemma":[0.000008520423,0.0001335618,0.0003220563,0.000001975429,0.000008439721,0.00004145303,0.000003633806,0.0004004402,0.9988159,0.000007756076,0.0002530936,0.000003175107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876544,0.001832261,0.009472397,0.00013268,0.00002641274,0.00009345528,0.00008622709,0.0000836614,0.0006186388],"genre_scores_gemma":[0.9837494,0.001156382,0.01342714,0.00009177757,0.00001268558,0.00007984046,0.0001332633,0.00003352335,0.001316067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001176846,"threshold_uncertainty_score":0.004469097,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.001774661095711281,"score_gpt":0.197743308054194,"score_spread":0.1959686469584827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}