{"id":"W2167470811","doi":"10.1093/intimm/dxh094","title":"Autoantibodies purified from therapeutic preparations of intravenous immunoglobulins (IVIg) induce the formation of autoimmune complexes in normal human serum: a role in the in vivo mechanisms of action of IVIg?","year":2004,"lang":"en","type":"article","venue":"International Immunology","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Héma-Québec","funders":"","keywords":"Autoantibody; Antibody; Immunology; Autoimmune disease; Immunoglobulin G; In vivo; Chemistry; Blot; Affinity chromatography; Medicine; Biochemistry; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002027882,0.0001050083,0.0003423973,0.0002772282,0.00002757859,0.000004254407,0.0002451118,0.00009698403,0.00004388031],"category_scores_gemma":[0.00003069214,0.0000745403,0.00006720555,0.000202389,0.0001445842,0.0001503599,0.00004314576,0.0001773633,0.000001137199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009682254,"about_ca_system_score_gemma":0.00007820809,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008998371,"about_ca_topic_score_gemma":0.004444066,"domain_scores_codex":[0.9988052,0.00009947117,0.000682985,0.0001038818,0.0001907202,0.0001177455],"domain_scores_gemma":[0.9991794,0.0001057524,0.0003908533,0.0002077989,0.0001115015,0.000004717308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004799131,0.001515182,0.00423727,0.00002307995,0.0002959891,0.00000852348,0.01310265,0.0007446106,0.9633915,0.01497134,8.859286e-7,0.001229013],"study_design_scores_gemma":[0.003625418,0.0005119487,0.5472768,0.0002036465,0.00004349294,0.00004321749,0.004379121,0.0004888173,0.4155962,0.02775708,0.00001413306,0.00006008821],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975428,0.0004864667,0.0002870255,0.000568983,0.00008983152,0.0003969201,0.00006914118,0.000005532072,0.0005532755],"genre_scores_gemma":[0.9995528,0.0001403199,0.000120594,0.00003124971,0.000004866128,0.00003292428,0.00009882503,0.000006160519,0.00001221556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5477953,"threshold_uncertainty_score":0.9976008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0247141957497123,"score_gpt":0.3017844953020424,"score_spread":0.2770702995523301,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}