{"id":"W2167470811","doi":"10.1093/intimm/dxh094","title":"Autoantibodies purified from therapeutic preparations of intravenous immunoglobulins (IVIg) induce the formation of autoimmune complexes in normal human serum: a role in the in vivo mechanisms of action of IVIg?","year":2004,"lang":"en","type":"article","venue":"International Immunology","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Héma-Québec","funders":"","keywords":"Autoantibody; Antibody; Immunology; Autoimmune disease; Immunoglobulin G; In vivo; Chemistry; Blot; Affinity chromatography; Medicine; Biochemistry; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004515715,0.0005039998,0.000370634,0.0002578721,0.0001167624,0.0005650481,0.0002052627,0.0007315553,0.001592755],"category_scores_gemma":[0.0003399286,0.0001519807,0.0002514489,0.0001404182,0.0003519425,0.0002255808,0.0001856692,0.0006600347,0.0008311943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003425072,"about_ca_system_score_gemma":0.0002120806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003481375,"about_ca_topic_score_gemma":0.0002114077,"domain_scores_codex":[0.9996669,0.000108667,0.00002938367,0.00005876614,0.00007198682,0.0000642825],"domain_scores_gemma":[0.9997743,0.0000401593,0.00005509279,0.00004136918,0.00004611713,0.00004300081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001397465,0.00006039951,0.001199171,0.0001390455,0.00001950069,0.0002418053,0.0000375125,0.00002980245,0.9872019,0.0004760168,0.0002156364,0.01023949],"study_design_scores_gemma":[0.00005083624,0.0008349408,0.008114285,0.00004950239,0.00006129471,0.002099058,0.00004455302,0.0004654847,0.9751492,0.0004250799,0.01269877,0.0000071176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.899797,0.05736643,0.03223743,0.001802171,0.000761467,0.0001784402,0.0002470078,0.000515979,0.007094158],"genre_scores_gemma":[0.9829668,0.006941246,0.005563654,0.000496413,0.0001619285,0.00003741168,0.0003133881,0.00003124872,0.003487977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001592755,"threshold_uncertainty_score":0.005328298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0247141957497123,"score_gpt":0.3017844953020424,"score_spread":0.2770702995523301,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}