{"id":"W2167503985","doi":"10.1128/jvi.79.9.5799-5811.2005","title":"Tumorigenic Poxviruses Up-Regulate Intracellular Superoxide To Inhibit Apoptosis and Promote Cell Proliferation","year":2005,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; University of Alberta","keywords":"Biology; Myxoma virus; Intracellular; Programmed cell death; DNA laddering; Apoptosis; Superoxide; Virus; Molecular biology; Cell biology; Virology; DNA fragmentation; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001587436,0.0002762048,0.000188332,0.0002010356,0.0001080399,0.0003042412,0.0001060603,0.000246586,0.0007981505],"category_scores_gemma":[0.0001236221,0.0000820028,0.0001541198,0.00008561443,0.0001847523,0.0001808399,0.0001384918,0.0004840857,0.0002086214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001621882,"about_ca_system_score_gemma":0.0001199709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001650336,"about_ca_topic_score_gemma":0.0002449378,"domain_scores_codex":[0.999863,0.00003406478,0.00001192217,0.00001876905,0.00003876577,0.00003350379],"domain_scores_gemma":[0.9998705,0.00004862357,0.00002541274,0.00001799411,0.00001307205,0.00002438492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004474987,0.00004213575,0.000148256,0.00001485305,0.000001508912,0.00002169527,0.00001373004,0.00003838531,0.9985416,0.0001376511,0.00002225289,0.0009730809],"study_design_scores_gemma":[0.0000284466,0.0007754777,0.002844873,0.000005979017,0.000008771855,0.0001781351,0.00002459225,0.001113039,0.9925396,0.00007032449,0.002408638,0.000002209473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943517,0.001588568,0.002263435,0.00006245334,0.00002851104,0.00003782258,0.00006916146,0.00006069521,0.001537505],"genre_scores_gemma":[0.9960814,0.0006177208,0.001619803,0.00002404664,0.00001226437,0.00002726164,0.0001279668,0.000008550633,0.001481067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007981505,"threshold_uncertainty_score":0.00267005,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01077719954905517,"score_gpt":0.2690529505689819,"score_spread":0.2582757510199267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}