{"id":"W2167552313","doi":"10.1111/j.1468-3083.2004.01180.x","title":"Hyaluronic acid: a unique topical vehicle for the localized delivery of drugs to the skin","year":2005,"lang":"en","type":"review","venue":"Journal of the European Academy of Dermatology and Venereology","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":371,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Hyaluronic acid; Transdermal; Drug delivery; Pharmacology; Dermatology; Surgery","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001472536,0.0004550981,0.0003057649,0.0007650757,0.000184282,0.0005394927,0.000233531,0.0005044768,0.001193225],"category_scores_gemma":[0.00009211705,0.0001289599,0.0001958302,0.0006624439,0.0002239252,0.000711766,0.0002928952,0.0005840387,0.001063308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002345861,"about_ca_system_score_gemma":0.0002338605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003230661,"about_ca_topic_score_gemma":0.0004379544,"domain_scores_codex":[0.9999076,0.00001346842,0.000008791406,0.00001804389,0.00003950479,0.00001255926],"domain_scores_gemma":[0.9999672,0.000006292903,0.000009934023,0.000001489169,0.000008440268,0.000006670787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001493907,0.0001064559,0.0003827561,0.007217604,0.00005574689,0.001120295,0.0001475625,0.0004226918,0.3861286,0.005537928,0.01168475,0.5870463],"study_design_scores_gemma":[0.00001563316,0.0004437107,0.001994157,0.0004585898,0.00008305802,0.007462177,0.00008409561,0.0003440132,0.136519,0.0007533485,0.8518078,0.00003452455],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0120047,0.9683427,0.007874157,0.0004953409,0.0007359314,0.00006152882,0.0001485387,0.0001041403,0.010233],"genre_scores_gemma":[0.06061042,0.9125891,0.007778203,0.0005639605,0.0005385446,0.00006363974,0.0002538395,0.00002581962,0.01757655],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001193225,"threshold_uncertainty_score":0.003991723,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03020499803473864,"score_gpt":0.3339282385067472,"score_spread":0.3037232404720085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}