{"id":"W2167557320","doi":"10.2174/1871520614666140608150448","title":"Deoxypodophyllotoxin Isolated from Juniperus communis Induces Apoptosis in Breast Cancer Cells","year":2014,"lang":"en","type":"article","venue":"Anti-Cancer Agents in Medicinal Chemistry","topic":"Biological Activity of Diterpenoids and Biflavonoids","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton","funders":"Canadian Institutes of Health Research","keywords":"Apoptosis; Cancer; Lignan; MAPK/ERK pathway; Natural product; Cancer cell; Breast cancer; Traditional medicine; Biology; Chemistry; Medicine; Biochemistry; Botany; Signal transduction; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002545943,0.0003250093,0.0004402213,0.00003246506,0.00007358699,0.00002683701,0.0005875557,0.0004896924,0.0005960616],"category_scores_gemma":[0.0000289411,0.0002803819,0.00009605625,0.0002111381,0.0002322172,0.0000118028,0.0002330081,0.0005278512,0.000007557414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007061276,"about_ca_system_score_gemma":0.00005795329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003959819,"about_ca_topic_score_gemma":0.0002297548,"domain_scores_codex":[0.9981895,0.0001173662,0.0003883705,0.0006055788,0.0002295303,0.0004696567],"domain_scores_gemma":[0.9991953,0.00003557458,0.0001479248,0.000424173,0.00005127424,0.0001457355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001429906,0.0002369845,0.05773625,0.00004983866,0.0000501955,0.000003756287,0.00007135874,0.00003657674,0.9292389,3.251366e-7,0.0007517477,0.01168107],"study_design_scores_gemma":[0.001376381,0.00008441298,0.07762291,0.0002316558,0.00002399158,0.00000266641,0.0001390958,0.0002743614,0.9172196,0.00002498725,0.002603427,0.000396464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973275,0.0006413661,0.0000398456,0.0008558929,0.000228685,0.000134116,0.0001775718,0.00001606031,0.0005789277],"genre_scores_gemma":[0.9952151,0.00236215,0.00009065092,0.001394461,0.0005456829,0.00005903401,0.0001621043,0.00002634151,0.0001444709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01988666,"threshold_uncertainty_score":0.9999648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01656664435939113,"score_gpt":0.2774306142152526,"score_spread":0.2608639698558614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}