{"id":"W2167558493","doi":"10.1371/journal.pone.0055867","title":"Chronic Over-Expression of Heat Shock Protein 27 Attenuates Atherogenesis and Enhances Plaque Remodeling: A Combined Histological and Mechanical Assessment of Aortic Lesions","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Ottawa","funders":"Institute of Gender and Health; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies; University of Ottawa; Canadian Institutes of Health Research; Mitacs; Canada Research Chairs","keywords":"Hsp27; Apolipoprotein E; Heat shock protein; Lesion; Apolipoprotein B; Internal medicine; Medicine; Endocrinology; Hsp70; Cholesterol; Pathology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001897339,0.0001362619,0.0003198899,0.0000428053,0.00005735447,0.00001067072,0.0001339344,0.0001892263,0.00006457005],"category_scores_gemma":[0.0001484336,0.0001096742,0.00004141759,0.00005760373,0.0001457243,0.000007427223,0.0002749251,0.000117155,0.000001260191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003058152,"about_ca_system_score_gemma":0.0001222997,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009808769,"about_ca_topic_score_gemma":0.0000168398,"domain_scores_codex":[0.9986891,0.0001430628,0.0003132712,0.0003462761,0.0002824727,0.0002258424],"domain_scores_gemma":[0.9993483,0.00003756075,0.00006690162,0.0002902227,0.0001369548,0.0001200403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000530287,0.0004800825,0.001770606,0.0002396278,0.00005988167,5.593619e-7,0.00001052467,0.000004267791,0.9967378,0.00003912778,0.00001295821,0.0005915316],"study_design_scores_gemma":[0.0005488304,0.001423676,0.001698493,0.0002460559,0.00002709041,0.000001272689,0.00001574139,0.006278937,0.9894607,0.0001724571,0.00001244172,0.0001143054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967638,0.001246426,0.0006843944,0.0003494081,0.000005173994,0.0008958117,0.000009650451,0.000008254439,0.00003706632],"genre_scores_gemma":[0.9937486,0.0005565087,0.00533758,0.00001151565,0.00003213343,0.000175344,0.00001634457,0.0000160697,0.0001059028],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007277104,"threshold_uncertainty_score":0.4472386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03674870012275525,"score_gpt":0.2915443354299231,"score_spread":0.2547956353071678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}