{"id":"W2167564168","doi":"10.1002/prot.20802","title":"Binding site‐based classification of coronaviral papain‐like proteases","year":2005,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"Papain; Proteases; Virology; Chemistry; Computational biology; Biology; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007109097,0.0001269484,0.00009952801,0.00006281231,0.00006675924,0.00002013721,0.00005085604,0.000118759,0.00002710351],"category_scores_gemma":[0.00002842181,0.0001083188,0.0000407579,0.00007846647,0.000046742,0.000008311149,0.00002679727,0.00007096279,0.000003399517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001011349,"about_ca_system_score_gemma":0.00003270777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003246437,"about_ca_topic_score_gemma":0.00001473594,"domain_scores_codex":[0.999379,0.00001177582,0.0002457355,0.0001154312,0.0001177466,0.0001302897],"domain_scores_gemma":[0.9995973,0.000004286275,0.0001158371,0.0001687552,0.00005989725,0.00005398953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001060947,0.00002511579,0.002816311,0.0002237225,0.00002586154,7.024302e-8,0.00008408954,0.002073786,0.9492156,0.00007096145,0.0002268987,0.04513152],"study_design_scores_gemma":[0.002230359,0.001002695,0.03846556,0.00009573466,0.00009272851,0.00002677851,0.0003784235,0.1633128,0.7475058,0.00004944269,0.04619819,0.0006414028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.860465,0.000250612,0.1382804,0.00008188668,0.0001060713,0.0005035673,0.00007959351,0.00002636106,0.000206487],"genre_scores_gemma":[0.9735827,0.00001575124,0.02584051,0.00009744805,0.0001210577,0.00001719209,0.000251728,0.00001001987,0.00006360015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2017097,"threshold_uncertainty_score":0.4417114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008745804075274359,"score_gpt":0.2532463768164164,"score_spread":0.244500572741142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}