{"id":"W2167564168","doi":"10.1002/prot.20802","title":"Binding site‐based classification of coronaviral papain‐like proteases","year":2005,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"Papain; Proteases; Virology; Chemistry; Computational biology; Biology; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002845009,0.0005714622,0.0004984943,0.0008665864,0.0003079162,0.0006501829,0.0005754239,0.0004936163,0.001029314],"category_scores_gemma":[0.0005222201,0.0001728761,0.0006295008,0.0004532241,0.0002098155,0.0003717028,0.0003152168,0.0004203782,0.0005382513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002258554,"about_ca_system_score_gemma":0.0004622272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001156177,"about_ca_topic_score_gemma":0.001226428,"domain_scores_codex":[0.9998226,0.00003565976,0.00001845877,0.00005024906,0.00004103392,0.00003206253],"domain_scores_gemma":[0.9997901,0.00003855982,0.0000380231,0.00003683901,0.00004668569,0.00004971373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002351923,0.0005547949,0.06803402,0.0008952889,0.0002765745,0.0009126415,0.000562769,0.1307084,0.6945028,0.01122154,0.002519831,0.08745944],"study_design_scores_gemma":[0.0002823863,0.001775882,0.08668791,0.0001026831,0.0003364603,0.001799899,0.0006012245,0.7647017,0.1088752,0.01584385,0.01880572,0.0001871331],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9521408,0.001110854,0.03995644,0.00007182387,0.00002445071,0.0001972326,0.001047346,0.00100806,0.004443032],"genre_scores_gemma":[0.9371278,0.0007584833,0.0561746,0.00005979079,0.00001085361,0.0001465209,0.00433391,0.0001179345,0.001270105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001156177,"threshold_uncertainty_score":0.00344342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008745804075274359,"score_gpt":0.2532463768164164,"score_spread":0.244500572741142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}