{"id":"W2167566168","doi":"10.1093/jac/46.6.885","title":"Influence of the MexA-MexB-OprM multidrug efflux system on expression of the MexC-MexD-OprJ and MexE-MexF-OprN multidrug efflux systems in Pseudomonas aeruginosa","year":2000,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":123,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Efflux; Pseudomonas aeruginosa; Biology; Microbiology; Mutant; Multiple drug resistance; Siderophore; Pseudomonadales; Pseudomonadaceae; Cell biology; Bacteria; Antibiotics; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002288032,0.0002312622,0.0002962623,0.0001423577,0.0001733077,0.0005558395,0.0002291636,0.0002462908,0.0009753369],"category_scores_gemma":[0.000525366,0.0002038452,0.0001538982,0.0001398958,0.0003710273,0.0002168759,0.0003039774,0.0006039425,0.0002655342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003500201,"about_ca_system_score_gemma":0.0003077883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002013858,"about_ca_topic_score_gemma":0.002394228,"domain_scores_codex":[0.9996263,0.0001469043,0.00003439789,0.0000372786,0.00007705691,0.00007800941],"domain_scores_gemma":[0.999661,0.0001425405,0.00003754234,0.00003678248,0.00003102968,0.00009122802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004890203,0.00009819148,0.0004473807,0.00003068642,0.00000985108,0.000104095,0.00004094839,0.0001413303,0.9971687,0.00009645984,0.00005022233,0.001323008],"study_design_scores_gemma":[0.00004578018,0.001031645,0.0158792,0.00001446901,0.00002812748,0.0002964505,0.00009879848,0.002117516,0.9787617,0.00008029433,0.001622532,0.00002348167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984112,0.0005396422,0.000201084,0.00007404306,0.00001309947,0.000006495418,0.00009186589,0.000009926759,0.0006527246],"genre_scores_gemma":[0.9985274,0.0002363864,0.000314933,0.00003774209,0.000007007506,0.000007687606,0.0001541648,0.00001346338,0.0007010588],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002013858,"threshold_uncertainty_score":0.0040043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003635918591850331,"score_gpt":0.2123649467143415,"score_spread":0.2087290281224911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}