{"id":"W2167566168","doi":"10.1093/jac/46.6.885","title":"Influence of the MexA-MexB-OprM multidrug efflux system on expression of the MexC-MexD-OprJ and MexE-MexF-OprN multidrug efflux systems in Pseudomonas aeruginosa","year":2000,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":123,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Efflux; Pseudomonas aeruginosa; Biology; Microbiology; Mutant; Multiple drug resistance; Siderophore; Pseudomonadales; Pseudomonadaceae; Cell biology; Bacteria; Antibiotics; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000625272,0.0003486226,0.0006671319,0.00008954233,0.0001106243,0.00003824791,0.0008197416,0.0002964718,0.00001174649],"category_scores_gemma":[0.0000817601,0.0002109269,0.0003103172,0.0002166534,0.0003783605,0.00002758152,0.00009690373,0.0003481784,0.000001781229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000720949,"about_ca_system_score_gemma":0.0001524281,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001419854,"about_ca_topic_score_gemma":0.00001988792,"domain_scores_codex":[0.9974669,0.0003326837,0.001124515,0.0003419876,0.0004141133,0.0003198333],"domain_scores_gemma":[0.9977997,0.00008130186,0.001123244,0.0006990497,0.0002167515,0.00007995709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007477495,0.0001917027,0.02825564,0.0002564159,0.00007533217,0.000003746272,0.0003540247,0.003961185,0.9650568,0.000009457267,0.0007733402,0.0003146104],"study_design_scores_gemma":[0.002540128,0.0001556584,0.08495512,0.0020677,0.00003080969,0.0001543025,0.0001417172,0.0000866607,0.908262,0.000002327654,0.001397949,0.0002056059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983518,0.0003772428,0.00001798695,0.0002314045,0.0003475726,0.0005024213,0.000038474,0.000005697461,0.0001273695],"genre_scores_gemma":[0.9980171,0.0009348002,0.0003554703,0.0001974083,0.0002032206,0.000001834199,0.000002720295,0.00004607597,0.0002413167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05679477,"threshold_uncertainty_score":0.8601351,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003635918591850331,"score_gpt":0.2123649467143415,"score_spread":0.2087290281224911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}