{"id":"W2167571882","doi":"10.1093/annonc/mdt066","title":"Global, multicenter, randomized, phase II trial of gemcitabine and gemcitabine plus AGS-1C4D4 in patients with previously untreated, metastatic pancreatic cancer","year":2013,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Cancer Foundation; Juravinski Cancer Centre; Sunnybrook Health Science Centre","funders":"National Cancer Institute; Astellas Pharma; Genentech; Amgen","keywords":"Gemcitabine; Medicine; Clinical endpoint; Pancreatic cancer; Internal medicine; Adenocarcinoma; Phases of clinical research; Oncology; Gastroenterology; Deoxycytidine; Chemotherapy; Cancer; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001748481,0.001912527,0.003119917,0.0004454825,0.0004117186,0.001377746,0.0009370404,0.001243661,0.004884965],"category_scores_gemma":[0.001178463,0.0007250897,0.00229006,0.0007097945,0.001814631,0.001448908,0.0007780274,0.003746971,0.0008844205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001150446,"about_ca_system_score_gemma":0.001643794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001133182,"about_ca_topic_score_gemma":0.004769101,"domain_scores_codex":[0.9994398,0.0003393277,0.00001941905,0.00009842112,0.00002329697,0.00007966829],"domain_scores_gemma":[0.9993669,0.0001285213,0.0001235586,0.00005110271,0.00002591346,0.0003039735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9579362,0.006363518,0.002604774,0.0004891524,0.001840521,0.00004953902,0.00007877121,0.001310776,0.003158137,0.0001906657,0.002172325,0.02380563],"study_design_scores_gemma":[0.9301236,0.06292799,0.003885343,0.00003389812,0.0007198786,0.00006334874,0.00005752444,0.0004308569,0.0003637896,0.0002547234,0.001120805,0.0000183157],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880996,0.004772875,0.0005290873,0.001285135,0.0005077957,0.001146203,0.001002545,0.0001164854,0.002540296],"genre_scores_gemma":[0.9836791,0.003598826,0.002152046,0.002161891,0.0003942433,0.001743237,0.002933099,0.00006193433,0.003275675],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004884965,"threshold_uncertainty_score":0.01634181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04994793834298716,"score_gpt":0.4032117858356602,"score_spread":0.353263847492673,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}