{"id":"W2167573905","doi":"10.1016/j.clinthera.2005.09.007","title":"Incidence of infection during efalizumab therapy for psoriasis: Analysis of the clinical trial experience","year":2005,"lang":"en","type":"review","venue":"Clinical Therapeutics","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":55,"is_retracted":false,"has_abstract":false,"ca_institutions":"Royal Victoria Hospital; Dalhousie University","funders":"Genentech","keywords":"Efalizumab; Medicine; Psoriasis; Placebo; Incidence (geometry); Clinical trial; Adverse effect; Internal medicine; Randomized controlled trial; Immunology; Plaque psoriasis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007846666,0.0004257243,0.002527132,0.001355516,0.0001431014,0.001451815,0.0008361552,0.0008030897,0.000740081],"category_scores_gemma":[0.00836283,0.0002235945,0.0009294261,0.002678406,0.0005348832,0.0008758824,0.0003334443,0.0008171219,0.000176458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008837917,"about_ca_system_score_gemma":0.001407968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006496326,"about_ca_topic_score_gemma":0.001048502,"domain_scores_codex":[0.9964646,0.001207207,0.0007343766,0.0004722968,0.001023423,0.00009803629],"domain_scores_gemma":[0.9887289,0.006648588,0.002852184,0.0002370627,0.001289198,0.000244007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.002467412,0.0001317473,0.02538806,0.01466147,0.001555172,0.000257331,0.0001751327,0.0004548888,0.001083483,0.0008103973,0.004648061,0.9483668],"study_design_scores_gemma":[0.002435895,0.01072889,0.5083377,0.03253348,0.01516702,0.01682269,0.001168231,0.001792764,0.006002744,0.003438035,0.4011993,0.0003732916],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009839177,0.9884953,0.0003694543,0.0003344709,0.00009214332,0.00002347994,0.0001406293,0.000006367155,0.0006989388],"genre_scores_gemma":[0.06761838,0.9298326,0.001061127,0.0005301025,0.0002694706,0.00005755089,0.0003369495,0.00000774885,0.0002862021],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007846666,"threshold_uncertainty_score":0.04149765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.27534577022948,"score_gpt":0.4846407011721711,"score_spread":0.2092949309426911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}