{"id":"W2167657860","doi":"10.1093/jac/dkt543","title":"Unique combined penA/mtrR/porB mutations and NG-MAST strain types associated with ceftriaxone and cefixime MIC increases in a ‘susceptible’ Neisseria gonorrhoeae population","year":2014,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Disease Control Laboratory; University of Saskatchewan","funders":"National Research Council Canada","keywords":"Neisseria gonorrhoeae; MTRR; Cefixime; Ceftriaxone; Microbiology; Neisseriaceae; Biology; Population; Neisseria; Penicillin; Medicine; Antibiotics; Virology; Genetics; Bacteria; Genotype; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007901717,0.0001867837,0.0004317991,0.0004142483,0.0001456697,0.00005811126,0.0001052455,0.0001850323,0.00009645974],"category_scores_gemma":[0.0003019166,0.0001555551,0.00005234611,0.0003534756,0.0002303181,0.0002830896,0.00001972272,0.0004514506,0.00000472464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008625415,"about_ca_system_score_gemma":0.00008901848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004465289,"about_ca_topic_score_gemma":0.0003239931,"domain_scores_codex":[0.9987167,0.0003296722,0.0004388814,0.0002289337,0.00003300002,0.0002528807],"domain_scores_gemma":[0.9989307,0.0002648644,0.0003819443,0.0001400839,0.0002415239,0.00004089273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001110786,0.0004892653,0.1401411,0.0000184307,0.0002395321,0.000003237205,0.0002797505,0.00005913308,0.8556968,0.00008234714,0.0002506412,0.001628957],"study_design_scores_gemma":[0.009104098,0.001978507,0.92591,0.000242489,0.00006924255,0.0008761134,0.0001614087,0.00003069803,0.06044966,0.0003111711,0.0005622068,0.0003044064],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983766,0.0001935367,0.0001001498,0.0008628916,0.00008421514,0.0002735917,0.00002135613,0.00001977493,0.00006789582],"genre_scores_gemma":[0.9990559,0.0002378869,0.0002729439,0.0001130921,0.00004468978,0.000002682666,0.0000645538,0.00002768169,0.000180631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7952471,"threshold_uncertainty_score":0.6343352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007803306962625801,"score_gpt":0.2447797198471135,"score_spread":0.2369764128844877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}