{"id":"W2167728216","doi":"10.1586/ern.10.98","title":"Update on emerging therapies for multiple sclerosis","year":2010,"lang":"en","type":"article","venue":"Expert Review of Neurotherapeutics","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Multiple sclerosis; Neurology; Medicine; Neuroscience; Disease; Dementia; Psychiatry; Psychology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001958421,0.0002921612,0.0004263549,0.00009046685,0.0001779942,0.00003170664,0.0004960843,0.00005757792,0.0001436015],"category_scores_gemma":[0.0006034546,0.0002361733,0.0002718605,0.0002510403,0.0001056723,0.0000892646,0.00004990077,0.0002308161,0.00003243856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005208393,"about_ca_system_score_gemma":0.00002662209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":8.613521e-7,"about_ca_topic_score_gemma":0.000001335261,"domain_scores_codex":[0.9980919,0.0001658036,0.000477029,0.0005456423,0.000376318,0.0003433363],"domain_scores_gemma":[0.9981064,0.0008711419,0.0002438295,0.0006138323,0.00007243406,0.00009231842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004315882,0.0001608586,0.000008828655,0.0003405469,0.000005708326,0.000002545596,0.00005071789,0.000001375678,0.975069,0.004356501,0.0004664266,0.01949434],"study_design_scores_gemma":[0.0003178167,0.0002428799,0.00002734639,0.0004007452,0.00001234768,0.0000103046,0.000002813149,0.0002416076,0.7508592,0.00006252017,0.2476573,0.0001651138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.928683,0.02327338,0.009098839,0.01887232,0.01030273,0.00773032,0.0003250799,0.0007755025,0.0009388041],"genre_scores_gemma":[0.6988979,0.1831936,0.003107557,0.1137895,0.0003786981,0.0003307151,0.00000327605,0.000201809,0.00009698126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2471909,"threshold_uncertainty_score":0.9630866,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09957778579025102,"score_gpt":0.3364130180750727,"score_spread":0.2368352322848217,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}