{"id":"W2167762097","doi":"10.1016/j.jmb.2008.12.021","title":"The Collagen Binding Domain of Gelatinase A Modulates Degradation of Collagen IV by Gelatinase B","year":2008,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Vlaamse regering; Fonds Wetenschappelijk Onderzoek","keywords":"Gelatinases; Matrix metalloproteinase; MMP9; Chemistry; MMP2; Gelatinase; Gelatinase A; Type I collagen; Collagen receptor; Type IV collagen; Biochemistry; Cell biology; Molecular biology; Extracellular matrix; Biology; Receptor; Integrin; Endocrinology; Laminin; Downregulation and upregulation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001946681,0.0002286322,0.0001771386,0.0001544667,0.0001634112,0.000340786,0.0002810438,0.0003045097,0.001560376],"category_scores_gemma":[0.0003954442,0.0002207654,0.0002638791,0.0000990144,0.0002472091,0.0002740104,0.0001890284,0.0005277364,0.0004899486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004327548,"about_ca_system_score_gemma":0.0001744058,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009998983,"about_ca_topic_score_gemma":0.0007075944,"domain_scores_codex":[0.9998083,0.00004781009,0.00001814086,0.00002406708,0.00002492004,0.0000768166],"domain_scores_gemma":[0.9996597,0.0001108072,0.00007117057,0.0000370091,0.00002857641,0.00009278206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003131086,0.00001818411,0.000139254,0.00001295194,0.000003703212,0.00003613533,0.000006691903,0.00003482406,0.9990521,0.00007441676,0.00001563812,0.000292956],"study_design_scores_gemma":[0.00004647722,0.0001611418,0.008943878,0.000005562417,0.00001389171,0.0002815446,0.00003185589,0.001349056,0.988376,0.00007615125,0.0007096608,0.00000489027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974033,0.0006951753,0.001104312,0.00007419199,0.00001724335,0.000007964623,0.00006742437,0.00001165706,0.0006186665],"genre_scores_gemma":[0.9980228,0.0002562026,0.0005929346,0.00003994415,0.000008544248,0.00001079673,0.0001547244,0.0000100651,0.0009039082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001560376,"threshold_uncertainty_score":0.005219996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007637481073729528,"score_gpt":0.2384335716813542,"score_spread":0.2307960906076247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}