{"id":"W2167790146","doi":"10.3390/pathogens1010012","title":"Roles for wbtC, wbtI, and kdtA Genes in Lipopolysaccharide Biosynthesis, Protein Glycosylation, Virulence, and Immunogenicity in Francisella tularensis Strain SCHU S4","year":2012,"lang":"en","type":"article","venue":"Pathogens","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Institute for Biological Sciences","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Francisella tularensis; Immunogenicity; Virulence; Microbiology; Gene; Lipopolysaccharide; Biology; Glycosylation; Strain (injury); Virology; Genetics; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001084065,0.0003604857,0.0001650902,0.0002041299,0.000133381,0.0002038061,0.0001823138,0.0002165438,0.0004671223],"category_scores_gemma":[0.0002219801,0.0001224549,0.0001874359,0.0001149443,0.0003114681,0.0001757953,0.000239194,0.0003501607,0.0002319654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003163111,"about_ca_system_score_gemma":0.0002683372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002165928,"about_ca_topic_score_gemma":0.001908597,"domain_scores_codex":[0.9999005,0.0000173778,0.00001504883,0.00001385126,0.00003002423,0.0000232185],"domain_scores_gemma":[0.9997749,0.000052421,0.0000811208,0.0000246264,0.00002819389,0.00003868003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006173908,0.00001286608,0.000473891,0.000007078525,0.00000144254,0.00003197083,0.00001158349,0.00005027165,0.9988995,0.00003790577,0.000003842997,0.0004080127],"study_design_scores_gemma":[0.000009921853,0.0001877745,0.006747236,0.000004218312,0.00001399846,0.0002766265,0.00006784612,0.001134045,0.991174,0.00004273442,0.0003348175,0.000006759828],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990655,0.00007738178,0.0006585318,0.00001463491,0.000001894309,0.000003633678,0.00004819769,0.000009701912,0.0001205098],"genre_scores_gemma":[0.9974699,0.00007458971,0.001415135,0.00001018618,0.000001701559,0.00001182436,0.0003325616,0.00001401686,0.000670116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002165928,"threshold_uncertainty_score":0.004306614,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0123693355726447,"score_gpt":0.2519541292992797,"score_spread":0.239584793726635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}