{"id":"W2167795826","doi":"10.1136/annrheumdis-2013-203696","title":"Effect of certolizumab pegol on signs and symptoms in patients with psoriatic arthritis: 24-week results of a Phase 3 double-blind randomised placebo-controlled study (RAPID-PsA)","year":2013,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":458,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland; Nexus Clinical Research (Canada)","funders":"UCB Pharma; Astellas Pharma; Celgene; Biogen; Sanofi; National Center for Advancing Translational Sciences; Chugai Pharmaceutical; Amgen; Pfizer; Genentech; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Certolizumab pegol; Psoriatic arthritis; Placebo; Double blind; Arthritis; Internal medicine; Psoriasis; Dermatology; Gastroenterology; Rheumatoid arthritis; Adalimumab; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002081248,0.0003122907,0.001646584,0.0001882581,0.00006562133,0.00001448833,0.0001289367,0.00004257907,0.00005032363],"category_scores_gemma":[0.0008271254,0.0001693116,0.0002439631,0.000237086,0.0001810587,0.00009711752,0.00005869618,0.00007818259,0.000003292443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000154874,"about_ca_system_score_gemma":0.00005667992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002968134,"about_ca_topic_score_gemma":0.00002880931,"domain_scores_codex":[0.9974907,0.000370957,0.0009650337,0.0002855162,0.0006143611,0.0002734279],"domain_scores_gemma":[0.9972376,0.001202063,0.0006747163,0.0005175334,0.0002245173,0.0001435195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8935471,0.01524493,0.031453,0.000646821,0.002662418,0.00002061438,0.001207335,0.0000167918,0.000008648903,0.000007550691,0.0002092438,0.05497552],"study_design_scores_gemma":[0.8927785,0.03647957,0.0650386,0.003659682,0.0009853169,0.000003178598,0.0003575075,0.00008186013,0.0004300953,0.00004133653,6.806511e-7,0.000143638],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987255,0.001737275,4.172497e-7,0.0001904882,0.00007387716,0.01044173,0.0001300598,0.00001256883,0.0001585723],"genre_scores_gemma":[0.9987628,0.0002655664,0.000005260606,0.00001686392,0.000008670905,0.0008612933,0.00002442482,0.00002394865,0.00003112764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05483188,"threshold_uncertainty_score":0.6904325,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02195920689164618,"score_gpt":0.298565301832091,"score_spread":0.2766060949404448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}