{"id":"W2167795826","doi":"10.1136/annrheumdis-2013-203696","title":"Effect of certolizumab pegol on signs and symptoms in patients with psoriatic arthritis: 24-week results of a Phase 3 double-blind randomised placebo-controlled study (RAPID-PsA)","year":2013,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":458,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland; Nexus Clinical Research (Canada)","funders":"UCB Pharma; Astellas Pharma; Celgene; Biogen; Sanofi; National Center for Advancing Translational Sciences; Chugai Pharmaceutical; Amgen; Pfizer; Genentech; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Certolizumab pegol; Psoriatic arthritis; Placebo; Double blind; Arthritis; Internal medicine; Psoriasis; Dermatology; Gastroenterology; Rheumatoid arthritis; Adalimumab; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003290378,0.001820704,0.003996201,0.0005305232,0.000490663,0.0009809602,0.0008966709,0.00248186,0.004749945],"category_scores_gemma":[0.002322688,0.0008679538,0.002208608,0.0004118414,0.001217409,0.001167345,0.0004055114,0.002440233,0.0009410213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004813941,"about_ca_system_score_gemma":0.0009244781,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003881323,"about_ca_topic_score_gemma":0.0007967474,"domain_scores_codex":[0.9987319,0.000726887,0.0001082547,0.0001799688,0.0001230249,0.0001300516],"domain_scores_gemma":[0.9982425,0.0004562243,0.0005191534,0.0001434384,0.0001377767,0.0005008009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9511067,0.01434633,0.0006777538,0.0008546773,0.0008395375,0.00006220051,0.00005774169,0.0002466199,0.006474606,0.00002986454,0.0004994893,0.02480447],"study_design_scores_gemma":[0.8428051,0.1534269,0.00260405,0.00002132315,0.0002371952,0.00003924984,0.000009895449,0.0001470255,0.0004316668,0.00003540994,0.0002276974,0.00001456459],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848381,0.008124147,0.0007519077,0.0004486,0.000334873,0.00356551,0.0008506712,0.0001730503,0.0009131645],"genre_scores_gemma":[0.9871106,0.003123541,0.002157033,0.0009572166,0.0005658244,0.003592655,0.0008820046,0.00003443575,0.001576799],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004749945,"threshold_uncertainty_score":0.01740146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02195920689164618,"score_gpt":0.298565301832091,"score_spread":0.2766060949404448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}