{"id":"W2167849700","doi":"10.1111/j.1528-1167.2010.02573.x","title":"Generic products of antiepileptic drugs: A perspective on bioequivalence and interchangeability","year":2010,"lang":"en","type":"review","venue":"Epilepsia","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"U.S. Food and Drug Administration; American Academy of Neurology","keywords":"Interchangeability; Bioequivalence; Medicine; Perspective (graphical); Antiepileptic drug; Epilepsy; Pharmacology; Computer science; Pharmacokinetics; Artificial intelligence; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005654997,0.0003684648,0.001675606,0.0001271867,0.00006625614,0.00001391305,0.0001529185,0.0002275565,0.0001345263],"category_scores_gemma":[0.001377706,0.0002475396,0.0002359514,0.0003728801,0.0004409404,0.00006245232,0.0001868278,0.001033186,0.0000521485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001343018,"about_ca_system_score_gemma":0.0001617325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004287182,"about_ca_topic_score_gemma":0.00000180757,"domain_scores_codex":[0.9981239,0.0002083408,0.000459003,0.0006538286,0.000270018,0.000284855],"domain_scores_gemma":[0.998165,0.0005980091,0.0003655636,0.0005087583,0.0002060362,0.0001566942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009897693,0.0002756354,0.00004552229,0.02228646,0.0002607111,0.00001817735,0.0005360016,4.577477e-9,0.00001990848,0.0006296178,0.0006096855,0.9752193],"study_design_scores_gemma":[0.0002430757,0.0005912891,0.0001786102,0.005499247,0.001638333,0.00006725435,0.0001951942,0.000003851542,0.00002881273,0.00006928144,0.9912629,0.00022215],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007554438,0.9909219,0.000002458338,0.001177319,0.0004139037,0.001214996,0.00005063565,0.00003154919,0.005431839],"genre_scores_gemma":[0.001787043,0.9969429,0.0003433875,0.0001678564,0.0004399182,0.00006799122,0.00001158364,0.00003410587,0.0002052198],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9906532,"threshold_uncertainty_score":0.9999977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1565407132288346,"score_gpt":0.4457691724349838,"score_spread":0.2892284592061492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}