{"id":"W2167863566","doi":"10.1002/iub.436","title":"Protonation of histidine 55 affects the oxygen access to heme in the alpha chain of the hemoglobin from the Antarctic fish <i>Trematomus bernacchii</i>","year":2011,"lang":"en","type":"article","venue":"IUBMB Life","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Tellabs (Canada)","funders":"","keywords":"Histidine; Protonation; Heme; Hemoglobin; Bohr effect; Fish <Actinopterygii>; Alpha (finance); Chemistry; Alpha chain; Oxygen; Biochemistry; Biophysics; Stereochemistry; Biology; Fishery; Gene; Organic chemistry; Psychology; Amino acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004531625,0.0001226099,0.00006322214,0.00005073095,0.0001329714,0.0001354408,0.0001574134,0.0001212532,0.001173079],"category_scores_gemma":[0.0001034649,0.00005553392,0.0001011691,0.0000482073,0.0002299351,0.0001232687,0.0001053103,0.0001731245,0.00009533869],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002587141,"about_ca_system_score_gemma":0.0001234361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003424562,"about_ca_topic_score_gemma":0.002456893,"domain_scores_codex":[0.9999813,0.000002969125,6.931391e-7,0.000004058003,0.00000379829,0.000007197172],"domain_scores_gemma":[0.999976,0.000008634676,0.000005879449,0.000001142047,0.000001896343,0.000006437309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001023193,0.0001054429,0.0103845,0.0001603313,0.00007029261,0.0005669111,0.0002108821,0.0146593,0.9656834,0.0008680786,0.0003505556,0.005917124],"study_design_scores_gemma":[0.0002402232,0.002069337,0.2226646,0.00004392063,0.0001909373,0.0009202956,0.0008395457,0.1431976,0.6254026,0.0009333887,0.0034235,0.00007402562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996663,0.0000356713,0.00008656919,0.00001468899,0.000001622615,5.401466e-7,0.000008886243,0.000002971787,0.0001826972],"genre_scores_gemma":[0.9997714,0.00004055161,0.00006157767,0.000006170156,7.607781e-7,6.174992e-7,0.00001737367,0.000001520623,0.0001000576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003424562,"threshold_uncertainty_score":0.006809235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02179627856997172,"score_gpt":0.2439984096534108,"score_spread":0.2222021310834391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}