{"id":"W2167875128","doi":"10.1038/emboj.2009.205","title":"The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding","year":2009,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":164,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; American Heart Association","keywords":"Follistatin; Biology; Myostatin; Receptor; Heparin; Plasma protein binding; Cell biology; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001005251,0.0003289215,0.0002977736,0.0001361972,0.0002438852,0.0004616499,0.0005635827,0.0004568031,0.002079512],"category_scores_gemma":[0.0001398483,0.0001579184,0.0001853692,0.0001569062,0.0002828608,0.0005584054,0.0002609775,0.0007632566,0.0006628768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000738645,"about_ca_system_score_gemma":0.0003796186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00101274,"about_ca_topic_score_gemma":0.0009754089,"domain_scores_codex":[0.9999619,0.00000455292,0.000002451221,0.00001336708,0.000007276274,0.00001045322],"domain_scores_gemma":[0.9999475,0.000007348457,0.00001380106,0.000004657846,0.000007714892,0.00001888427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001086213,0.0001114342,0.001609059,0.0001744396,0.00003872497,0.0009698867,0.0001439157,0.004075458,0.9551904,0.01513955,0.001336116,0.0201249],"study_design_scores_gemma":[0.0001858205,0.0008816199,0.01557024,0.00005301246,0.0001330747,0.003537735,0.0003409991,0.05506164,0.869123,0.01004035,0.04496688,0.0001055951],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9708382,0.004916975,0.01740924,0.0009822121,0.000130844,0.0000373084,0.0004182395,0.0001855341,0.005081376],"genre_scores_gemma":[0.9824358,0.001701508,0.005847503,0.0003608532,0.00003189277,0.00001504724,0.0007889994,0.00003132486,0.008787092],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002079512,"threshold_uncertainty_score":0.006956697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01048275675358503,"score_gpt":0.2655345039614185,"score_spread":0.2550517472078335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}