{"id":"W2167937389","doi":"10.1111/j.1574-695x.2007.00317.x","title":"Posttranscriptional gene expression regulation in CpG-activated macrophages depends on FXR1P RNA-binding protein","year":2007,"lang":"en","type":"article","venue":"FEMS Immunology & Medical Microbiology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"TLR9; Biology; Chemokine; Tumor necrosis factor alpha; Gene expression; Messenger RNA; TLR7; Molecular biology; Lipopolysaccharide; RNA; CpG site; Regulation of gene expression; Receptor; Cell biology; RNA-binding protein; Toll-Like Receptor 9; Proinflammatory cytokine; Toll-like receptor; Gene; Inflammation; Innate immune system; Immunology; Biochemistry; DNA methylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002615055,0.000261275,0.0002474956,0.0002181751,0.0001506643,0.0002864119,0.0001082421,0.0002716131,0.001062747],"category_scores_gemma":[0.0001321567,0.0001305266,0.0002601735,0.0001051425,0.0003218168,0.0001843587,0.0002056306,0.0004367678,0.0005255085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002265499,"about_ca_system_score_gemma":0.0001465148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002399233,"about_ca_topic_score_gemma":0.0002899313,"domain_scores_codex":[0.9997801,0.00004206395,0.00001505968,0.00007130517,0.00005104482,0.00004049643],"domain_scores_gemma":[0.9998382,0.00002867437,0.00007207534,0.00001630868,0.00002182201,0.0000228842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000721715,0.000004935955,0.0001197864,0.00001727363,0.000001669144,0.00002952735,0.00001156897,0.00001274148,0.999191,0.00004548033,0.00001035865,0.0004834963],"study_design_scores_gemma":[0.000009876859,0.0001339892,0.01070436,0.00001108143,0.000009854494,0.0002279475,0.00004762903,0.0005411211,0.9870058,0.00008020848,0.001223314,0.000004686559],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886862,0.003702725,0.005906507,0.0001738123,0.00003531716,0.00001668327,0.0003381214,0.00008393591,0.001056585],"genre_scores_gemma":[0.9914961,0.001326561,0.003613124,0.00008706204,0.0000220074,0.00004503824,0.0004657536,0.00003025109,0.002914143],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001062747,"threshold_uncertainty_score":0.003555238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009943668006959082,"score_gpt":0.267764291763995,"score_spread":0.257820623757036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}