{"id":"W2167952434","doi":"10.1128/iai.00005-10","title":"Fine-Tuning Synthesis of<i>Yersinia pestis</i>LcrV from Runaway-Like Replication Balanced-Lethal Plasmid in a<i>Salmonella enterica</i>Serovar Typhimurium Vaccine Induces Protection against a Lethal<i>Y. pestis</i>Challenge in Mice","year":2010,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Yersinia bacterium, plague, ectoparasites research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Petroleum Technology Research Centre","keywords":"Biology; Plasmid; Yersinia pestis; Virology; Salmonella enterica; Microbiology; Salmonella; Virulence; Molecular biology; Gene; Genetics; Bacteria","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006595515,0.0002576619,0.0003341576,0.0002865371,0.0001280182,0.00004223069,0.0002021193,0.0003964699,0.00002882051],"category_scores_gemma":[0.000684474,0.0002837218,0.00007135906,0.0003875507,0.0001050264,0.00004509899,0.000177676,0.0008279986,0.000006929872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005432565,"about_ca_system_score_gemma":0.00008828754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004609083,"about_ca_topic_score_gemma":0.00391495,"domain_scores_codex":[0.9981017,0.0003679558,0.0004701139,0.0005706559,0.0001696343,0.0003199611],"domain_scores_gemma":[0.9987921,0.0001346868,0.0002405049,0.0005895262,0.0001468757,0.00009631641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00028838,0.0002755123,0.1021219,0.00005623368,0.00002757959,0.000005201417,0.0001754558,0.00003975082,0.8910726,0.000002623214,0.00003683009,0.005897968],"study_design_scores_gemma":[0.0009251802,0.000221591,0.5248618,0.0001031625,0.00001312865,0.00003511732,0.00006072923,0.0005170966,0.4715628,0.00002051499,0.001428104,0.000250869],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979635,0.0001693176,0.0001444235,0.0002198752,0.0002951019,0.0004661872,0.00003380404,0.00003073535,0.0006770182],"genre_scores_gemma":[0.9987164,0.0005016606,0.0002839229,0.00004292172,0.0001138338,0.0001124646,0.0001738294,0.00003105401,0.00002395509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4227398,"threshold_uncertainty_score":0.9999615,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01408100955576868,"score_gpt":0.2622818516199552,"score_spread":0.2482008420641865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}