{"id":"W2167961763","doi":"10.1111/j.1365-2184.2005.00349.x","title":"Adenosine and deoxyadenosine induces apoptosis in oestrogen receptor‐positive and ‐negative human breast cancer cells via the intrinsic pathway","year":2005,"lang":"en","type":"article","venue":"Cell Proliferation","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"CancerCare Manitoba Foundation; Manitoba Health Research Council","keywords":"EHNA; Deoxyadenosine; Adenosine A3 receptor; Adenosine; Purinergic signalling; Adenosine Deaminase Inhibitor; Adenosine kinase; Adenosine receptor; Cancer research; Adenosine A2B receptor; Adenosine deaminase; Cancer cell; Biology; Apoptosis; Chemistry; Internal medicine; Endocrinology; Receptor; Biochemistry; Agonist; Cancer; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001014239,0.000174774,0.00019532,0.000107297,0.00009721167,0.0001715496,0.00008665941,0.0001479166,0.0007183254],"category_scores_gemma":[0.00009338294,0.00008529329,0.0001674063,0.0001083715,0.00006859822,0.00009751109,0.00009097539,0.0002158821,0.0002152817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000107976,"about_ca_system_score_gemma":0.00008906784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000282288,"about_ca_topic_score_gemma":0.0007091438,"domain_scores_codex":[0.9998863,0.00002669389,0.0000124404,0.0000177314,0.0000374502,0.00001950149],"domain_scores_gemma":[0.9999534,0.00001126941,0.00001138751,0.000007758416,0.00001025256,0.000005899321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001514737,0.00003128629,0.0004780624,0.00009379013,0.00001345819,0.0001079502,0.00002660242,0.00005115013,0.9962072,0.00005757856,0.00003484741,0.002746617],"study_design_scores_gemma":[0.00002477004,0.0008450233,0.009328732,0.00001133424,0.00003158911,0.0008815386,0.00004316019,0.0003595827,0.9838051,0.00003428527,0.004631262,0.000003648365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981986,0.0139634,0.001347607,0.00007961637,0.00003428747,0.0000237547,0.0002861831,0.00001792793,0.002261143],"genre_scores_gemma":[0.9923568,0.004322898,0.001077435,0.0000594735,0.00001184934,0.00002727753,0.0004311807,0.000003113001,0.001710013],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007183254,"threshold_uncertainty_score":0.002403021,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006791763026059243,"score_gpt":0.2254031995270049,"score_spread":0.2186114365009456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}