{"id":"W2167965268","doi":"10.1158/2159-8290.cd-14-1346","title":"Turning Telomerase into a Jekyll and Hyde Case?","year":2015,"lang":"en","type":"letter","venue":"Cancer Discovery","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Telomerase; Telomere; Guanine; DNA; Enzyme; Nucleotide; Chromosome; Biochemistry; Biology; Cell biology; Chemistry; Genetics; Molecular biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002042844,0.0006770452,0.001086117,0.0003434629,0.0001657534,0.0001953149,0.0001907217,0.0007726361,0.0001871997],"category_scores_gemma":[0.000159723,0.0005767925,0.0002040371,0.0003162202,0.0003576774,0.0004374223,0.0001648343,0.002124287,0.00005381231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005467248,"about_ca_system_score_gemma":0.001072146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002924593,"about_ca_topic_score_gemma":0.0003140439,"domain_scores_codex":[0.997004,0.00009365196,0.0005113199,0.0009999615,0.0006540047,0.0007370576],"domain_scores_gemma":[0.9982533,0.0001469664,0.0002621252,0.0007962972,0.0001907482,0.0003505711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001365432,0.00003391451,0.004944413,0.001395913,0.0002430937,0.0359577,0.001122361,0.000003518879,0.0005233304,0.000005406353,0.9459761,0.009657642],"study_design_scores_gemma":[0.001544959,0.000183753,0.0004886413,0.001323343,0.0006106585,0.006247362,0.0003799679,0.00005575074,0.0004377299,0.0001608011,0.9877076,0.000859392],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.5562723,0.05734196,0.0001116821,0.3775546,0.0032863,0.001370459,0.0005281399,0.0003307338,0.003203847],"genre_scores_gemma":[0.1395524,0.004831515,0.0004600929,0.7980249,0.01890935,0.0003401655,0.0009601739,0.0003779161,0.03654352],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.4204703,"threshold_uncertainty_score":0.9996684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0293652955356815,"score_gpt":0.2986595993283567,"score_spread":0.2692943037926752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}