{"id":"W2167980095","doi":"10.1016/j.ajpath.2011.07.002","title":"Silencing of the Imprinted DLK1-MEG3 Locus in Human Clinically Nonfunctioning Pituitary Adenomas","year":2011,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Jarislowsky Foundation","keywords":"MEG3; Gene silencing; Genomic imprinting; Cancer research; Medicine; Biology; Genetics; Gene; DNA methylation; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001323037,0.0002220722,0.0002929404,0.0007223216,0.0003999818,0.0004232418,0.0002011484,0.0002472939,0.00106637],"category_scores_gemma":[0.0004606327,0.0001741533,0.0001917426,0.0003525213,0.0004625674,0.00009893059,0.0002854801,0.0002289455,0.0002139532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004937989,"about_ca_system_score_gemma":0.0002949453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003647259,"about_ca_topic_score_gemma":0.003607051,"domain_scores_codex":[0.9998755,0.00001994791,0.00001429613,0.00002700636,0.0000370982,0.00002610675],"domain_scores_gemma":[0.9997138,0.0001285196,0.00004620352,0.00003310587,0.00002481204,0.00005342637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006174109,0.00002257186,0.01701382,0.0000373662,0.00002004923,0.006307487,0.000281979,0.0001907585,0.9721644,0.0002890146,0.0001185372,0.002936501],"study_design_scores_gemma":[0.0001690126,0.0005575071,0.4380397,0.0000113845,0.0001874095,0.05126223,0.001292614,0.002427305,0.4990264,0.001129743,0.005847162,0.00004958157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982698,0.0004212491,0.0003402726,0.00005103785,0.000007270843,0.000004671677,0.0001695069,0.00001990112,0.000716317],"genre_scores_gemma":[0.9995197,0.00007380841,0.00008337117,0.000008412701,0.000002181114,0.000002272158,0.00009992774,0.000005757809,0.0002046871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003647259,"threshold_uncertainty_score":0.007252097,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01393804012214764,"score_gpt":0.2548638972049951,"score_spread":0.2409258570828475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}