{"id":"W2167985599","doi":"10.1371/journal.pone.0000472","title":"Short RNA Guides Cleavage by Eukaryotic RNase III","year":2007,"lang":"en","type":"article","venue":"PLoS ONE","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Genome Canada","keywords":"RNA silencing; RNA; RNase P; Biology; Non-coding RNA; Ribonuclease III; RNA editing; RNA interference; RNase H; Cell biology; RNA-induced transcriptional silencing; RNase MRP; Cleavage (geology); Molecular biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000138169,0.0001039711,0.0001022919,0.00002750121,0.00005590743,0.00001706551,0.0001135393,0.00008780827,0.00007377473],"category_scores_gemma":[0.00006470031,0.0001045905,0.00005497197,0.00005734776,0.00004791863,0.000003276369,0.00004741933,0.00004333229,0.0000441532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001094403,"about_ca_system_score_gemma":0.00002120018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006875139,"about_ca_topic_score_gemma":0.000007831892,"domain_scores_codex":[0.9992001,0.00001592056,0.0001792327,0.0002182314,0.0001784256,0.0002080901],"domain_scores_gemma":[0.9994408,0.000007130036,0.00003085657,0.0002794471,0.00005357355,0.0001881363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001120721,0.0006033818,0.01184299,0.00001657604,0.00008111486,0.000009216837,0.000008944136,0.000001800872,0.9660075,0.00004439773,0.01967233,0.001599679],"study_design_scores_gemma":[0.0004604011,0.00009110462,0.02413675,0.00001536664,0.00005582715,0.000001538455,0.00002653906,0.00004647846,0.9722273,0.00002876665,0.002732037,0.0001778309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848464,0.0007134036,0.0007950164,0.000143232,0.00002766075,0.0001307505,0.00001585647,0.00002588155,0.01330184],"genre_scores_gemma":[0.9926029,0.000074885,0.0005651533,0.0006876155,0.0001913499,0.000005203699,0.0001867677,0.00001880999,0.005667259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0169403,"threshold_uncertainty_score":0.4265077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02233153400927239,"score_gpt":0.2450422208336031,"score_spread":0.2227106868243307,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}