{"id":"W2168030414","doi":"10.1016/j.plipres.2010.07.002","title":"Defective lipid transport and biosynthesis in recessive and dominant Stargardt macular degeneration","year":2010,"lang":"en","type":"review","venue":"Progress in Lipid Research","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Eye Institute; Canadian Institutes of Health Research","keywords":"ABCA4; Stargardt disease; Macular dystrophy; Macular degeneration; Biology; Retinal degeneration; Retinal pigment epithelium; Dystrophy; Genetics; ATP-binding cassette transporter; Retinal; Biochemistry; Gene; Medicine; Ophthalmology; Transporter; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00168793,0.0003261006,0.0006738314,0.0004632543,0.0001069082,0.00006130418,0.0002402314,0.0006619477,0.00001124581],"category_scores_gemma":[0.0002110348,0.000264547,0.00009453099,0.0003887393,0.0004621532,0.000009411296,0.0001833483,0.0007313556,0.000003003132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004081328,"about_ca_system_score_gemma":0.0003440029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001816149,"about_ca_topic_score_gemma":0.000218364,"domain_scores_codex":[0.9973904,0.0005269565,0.0004444442,0.0008044145,0.0003232786,0.0005104755],"domain_scores_gemma":[0.99931,0.00009080406,0.0001065842,0.0002709153,0.0001250547,0.00009669966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001051447,0.0000922628,0.01474144,0.003206928,0.00004052866,0.00002802108,0.0001141603,1.065347e-7,0.000281842,0.00003046721,0.00004875581,0.9813104],"study_design_scores_gemma":[0.0005539485,0.000206385,0.001492312,0.002499725,0.00004664503,0.00002870081,0.00007423333,0.000005794497,0.002686412,0.00003948015,0.9918864,0.0004799526],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04539068,0.9528378,0.00000687155,0.00004938878,0.0001064631,0.001216946,0.00001934998,0.000004329694,0.0003681544],"genre_scores_gemma":[0.01203446,0.9862705,0.000511106,0.000004872622,0.0001673286,0.0006528882,0.0002174277,0.00004649822,0.00009485621],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9918377,"threshold_uncertainty_score":0.9999807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04040084442592453,"score_gpt":0.3792789590433636,"score_spread":0.3388781146174391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}