{"id":"W2168090658","doi":"10.1016/j.molcel.2009.09.044","title":"SOCS1 Links Cytokine Signaling to p53 and Senescence","year":2009,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":140,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Suppressor of cytokine signaling 1; Transactivation; Biology; DNA damage; Senescence; Phosphorylation; Cell biology; Signal transduction; Cancer research; Cytokine; Suppressor; DNA; Genetics; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004108472,0.0005279082,0.0002682267,0.0006647717,0.0004342555,0.0008301985,0.0001751565,0.0004168367,0.004067069],"category_scores_gemma":[0.0004925907,0.0002163426,0.0004048729,0.000226268,0.0005791426,0.0004293726,0.0005991348,0.0008810339,0.0008482817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006553864,"about_ca_system_score_gemma":0.0004321603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003330552,"about_ca_topic_score_gemma":0.0005698383,"domain_scores_codex":[0.9996666,0.00007165966,0.00002233818,0.00004623484,0.00005610985,0.0001371258],"domain_scores_gemma":[0.9996573,0.00004523296,0.0001264108,0.00003035025,0.00004210695,0.00009869738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002403997,0.000121381,0.00393347,0.0002286391,0.00004362476,0.0005895013,0.0001230179,0.0003546569,0.970518,0.002190048,0.001302363,0.01819135],"study_design_scores_gemma":[0.0003548156,0.001958983,0.07360844,0.00008911471,0.0001355537,0.002063032,0.0005070301,0.003098281,0.8917049,0.004007835,0.02243175,0.00004032674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9712003,0.014776,0.002929814,0.002372905,0.0003317416,0.00003988421,0.0006801763,0.0002306835,0.007438508],"genre_scores_gemma":[0.9949556,0.001907868,0.000458562,0.0001706554,0.00009378661,0.00001896021,0.0002912988,0.00001168564,0.002091482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004067069,"threshold_uncertainty_score":0.01360565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01062448524089489,"score_gpt":0.2572585628915752,"score_spread":0.2466340776506803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}