{"id":"W2168090658","doi":"10.1016/j.molcel.2009.09.044","title":"SOCS1 Links Cytokine Signaling to p53 and Senescence","year":2009,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":140,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Suppressor of cytokine signaling 1; Transactivation; Biology; DNA damage; Senescence; Phosphorylation; Cell biology; Signal transduction; Cancer research; Cytokine; Suppressor; DNA; Genetics; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008369391,0.0001347069,0.0001828671,0.00009987221,0.0000663157,0.00003207873,0.0000526923,0.00009449989,0.00009726087],"category_scores_gemma":[0.00005575133,0.0001266808,0.00007808197,0.0001644241,0.00001615715,0.00003361873,0.00002430396,0.0002739988,0.00007113314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002682512,"about_ca_system_score_gemma":0.00003635916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002264189,"about_ca_topic_score_gemma":9.576439e-7,"domain_scores_codex":[0.9991598,0.00001771602,0.000175393,0.0002672117,0.0001666871,0.0002132478],"domain_scores_gemma":[0.9994345,0.00002292845,0.00003629502,0.0002213588,0.00007850932,0.0002064221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003806926,0.00008474257,0.0001256428,0.00001819711,0.000008093932,0.0001760333,0.0001464599,0.000083894,0.9940493,0.0001083552,0.0005208621,0.004640412],"study_design_scores_gemma":[0.0004968731,0.0005279058,0.0005449866,0.0001085811,0.00005192432,0.00006567001,0.00004401349,0.000418294,0.972961,0.00009609156,0.02453492,0.0001496978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9570604,0.000374712,0.0269922,0.003748044,0.00009572559,0.0002898816,0.000005901017,0.00009042082,0.01134269],"genre_scores_gemma":[0.9885168,0.00001556191,0.004927496,0.005991853,0.0001136332,0.000004390174,0.00001199554,0.00001717485,0.0004010668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03145641,"threshold_uncertainty_score":0.5165891,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01062448524089489,"score_gpt":0.2572585628915752,"score_spread":0.2466340776506803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}