{"id":"W2168128112","doi":"10.1038/sj.npp.1301476","title":"The Novel Cannabinoid CB1 Receptor Neutral Antagonist AM4113 Suppresses Food Intake and Food-Reinforced Behavior but Does not Induce Signs of Nausea in Rats","year":2007,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":160,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"National Institute on Drug Abuse; National Institutes of Health","keywords":"Inverse agonist; Cannabinoid receptor; Appetite; Cannabinoid; Agonist; Nausea; Antagonist; Malaise; Pharmacology; Rimonabant; Anorectic; Endocrinology; Internal medicine; Medicine; Receptor; Food intake","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006784063,0.0003597044,0.0005533671,0.000357691,0.000235431,0.00005485244,0.0003905909,0.0002518264,0.0001379044],"category_scores_gemma":[0.0001748117,0.0002500298,0.000138622,0.0005358774,0.0008211674,0.0001197971,0.0001794277,0.001057012,0.000006552119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009897154,"about_ca_system_score_gemma":0.0003342322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002507957,"about_ca_topic_score_gemma":0.0006385276,"domain_scores_codex":[0.9969639,0.0001483466,0.0008339086,0.0006187842,0.0004459374,0.0009891323],"domain_scores_gemma":[0.9984046,0.0001698255,0.0002228579,0.0004438958,0.0003201324,0.0004386424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002756268,0.0003748878,0.004702887,0.0001236656,0.00006686447,0.00007800154,0.0003131469,0.000005930739,0.9806675,0.0002785995,0.00747787,0.003154327],"study_design_scores_gemma":[0.006838785,0.00467719,0.146591,0.00002645808,0.0001142951,0.0001619447,0.000517521,0.00002512669,0.8056684,0.00000693705,0.03506785,0.0003045123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864924,0.0001951177,0.000009405862,0.009476572,0.001687524,0.001514998,0.0002027745,0.00004971093,0.0003714858],"genre_scores_gemma":[0.9934198,0.0003955593,0.00003577282,0.001869803,0.0003835683,0.0002195895,0.00001903858,0.00006889454,0.00358794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1749991,"threshold_uncertainty_score":0.9999952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02578981506567394,"score_gpt":0.3242388533866918,"score_spread":0.2984490383210179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}