{"id":"W2168132477","doi":"10.1016/j.cell.2009.12.027","title":"Drosophila Genome-wide Obesity Screen Reveals Hedgehog as a Determinant of Brown versus White Adipose Cell Fate","year":2010,"lang":"en","type":"article","venue":"Cell","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":374,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Princess Margaret Cancer Centre; Hospital for Sick Children; Ontario Institute for Cancer Research; University of Toronto","funders":"Österreichischen Akademie der Wissenschaften; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Centre National de la Recherche Scientifique; European Commission","keywords":"Biology; White (mutation); Drosophila (subgenus); Hedgehog; Genetics; Genome; White adipose tissue; Adipose tissue; Brown adipose tissue; Drosophila melanogaster; Evolutionary biology; Gene; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001101431,0.00043124,0.0002878933,0.0005713418,0.0003121846,0.0004530168,0.0003535672,0.0003131127,0.001621693],"category_scores_gemma":[0.0001113056,0.0003225035,0.0002645249,0.0002985203,0.0003746027,0.0001530778,0.000460996,0.0006501371,0.0003109163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005351614,"about_ca_system_score_gemma":0.0003138898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002629577,"about_ca_topic_score_gemma":0.01140619,"domain_scores_codex":[0.9998466,0.00001521988,0.00001179964,0.00004387607,0.00004814567,0.00003435576],"domain_scores_gemma":[0.9998435,0.00003598499,0.00005231078,0.00001118999,0.000009747376,0.00004725655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000111112,0.000009499922,0.0006101546,0.00001342987,0.00001029788,0.00009438546,0.000008421523,0.00007611112,0.9980919,0.0001239302,0.00006407902,0.0007867061],"study_design_scores_gemma":[0.00006114331,0.0001090463,0.04861627,0.00001049502,0.0001153315,0.0004980039,0.0001318628,0.002461179,0.9456779,0.0001280544,0.002171862,0.00001902648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941916,0.0004354239,0.001836521,0.0001199072,0.00002490744,0.00001481319,0.001386158,0.00009205524,0.001898615],"genre_scores_gemma":[0.9931238,0.0002889473,0.001836593,0.0001910052,0.000005046115,0.00001596133,0.0009909755,0.00007521411,0.003472321],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002629577,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02795998503694014,"score_gpt":0.2751182656821274,"score_spread":0.2471582806451872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}