{"id":"W2168143869","doi":"10.1016/s1016-8478(23)13056-1","title":"Calreticulin, Ca2+, and Calcineurin - Signaling from the Endoplasmic Reticulum","year":2004,"lang":"en","type":"article","venue":"Molecules and Cells","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":123,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research","funders":"","keywords":"Endoplasmic reticulum; Calreticulin; Cell biology; STIM1; Calcium signaling; Calcineurin; Biology; Signal transduction; Cytoplasm; Internal medicine; Medicine; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008328699,0.0001706565,0.0001162017,0.000009879269,0.0001266054,0.00005504812,0.0001333133,0.00009825599,0.00001393084],"category_scores_gemma":[0.00004357678,0.0001285613,0.00005426074,0.00004081005,0.0001757312,0.00000217781,0.0001352974,0.00009990148,0.000006850837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005669734,"about_ca_system_score_gemma":0.00004074664,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000160419,"about_ca_topic_score_gemma":0.00002447943,"domain_scores_codex":[0.9990923,0.00005060445,0.000152611,0.0003796855,0.0001115411,0.0002132166],"domain_scores_gemma":[0.9994929,0.0000305818,0.00004797276,0.0002725033,0.0000309158,0.0001250591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003364497,0.00002842555,0.0004786059,0.00000995988,0.0000303649,0.00003205077,0.0001292753,0.0005481236,0.9978758,0.0001967087,0.0004074252,0.0002296461],"study_design_scores_gemma":[0.0007029065,0.0001068329,0.0004203489,0.0000308883,0.00004972847,0.00001323769,0.0001314973,0.00006661283,0.9946071,0.000849598,0.002831974,0.0001893065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942858,0.003359371,0.001340983,0.0004851166,0.00009899773,0.0001419095,0.00006381419,0.00001397213,0.0002099938],"genre_scores_gemma":[0.9974315,0.0002725024,0.0007452061,0.001257238,0.0001434562,0.00001251192,0.00004765752,0.00002368517,0.00006630741],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003268701,"threshold_uncertainty_score":0.5242578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005546225001623398,"score_gpt":0.1983143788294025,"score_spread":0.1927681538277791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}