{"id":"W2168183743","doi":"10.1186/1471-2199-9-104","title":"The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals","year":2008,"lang":"en","type":"article","venue":"BMC Molecular Biology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":192,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Fonds Québécois de la Recherche sur la Nature et les Technologies; University of Minnesota; McKnight Foundation","keywords":"Biology; Gene; Genetics; Retrotransposon; Most recent common ancestor; Phylogenetic tree; Lineage (genetic); Evolutionary biology; Repertoire; Genome; Transposable element","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007688211,0.0001936033,0.0002759106,0.00008094468,0.0005780784,0.000009557009,0.0004760298,0.0002479623,0.00004623997],"category_scores_gemma":[0.0007882067,0.0001226179,0.0001446742,0.0003119941,0.0007745336,0.00006907523,0.00008167254,0.0002137342,0.00002357438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004165421,"about_ca_system_score_gemma":0.0001542873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000114494,"about_ca_topic_score_gemma":0.0000380128,"domain_scores_codex":[0.9980616,0.0007138349,0.0004698059,0.0003226506,0.00005028639,0.0003818232],"domain_scores_gemma":[0.998615,0.0005618699,0.0002682313,0.0004299882,0.0001203671,0.000004561652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006034293,0.0002019697,0.01024299,0.00001802111,0.00006186283,0.000003356203,0.001350966,0.00004604286,0.9826322,0.00393869,0.00005748393,0.0008429862],"study_design_scores_gemma":[0.01167162,0.001055751,0.2693146,0.0002216505,0.0001110966,0.0008730366,0.008414529,0.0002681988,0.688512,0.001658771,0.016935,0.0009638234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9330465,0.03759091,0.02770724,0.0002746529,0.0005463456,0.0007415669,0.00001710044,0.00002897055,0.00004668628],"genre_scores_gemma":[0.9985023,0.0002936642,0.0003726649,0.0002030173,0.000004309536,0.00009516737,0.0002232715,0.00001689036,0.0002887425],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2941203,"threshold_uncertainty_score":0.5000211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08195811886310804,"score_gpt":0.3031235811479566,"score_spread":0.2211654622848486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}