{"id":"W2168183743","doi":"10.1186/1471-2199-9-104","title":"The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals","year":2008,"lang":"en","type":"article","venue":"BMC Molecular Biology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":192,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Fonds Québécois de la Recherche sur la Nature et les Technologies; University of Minnesota; McKnight Foundation","keywords":"Biology; Gene; Genetics; Retrotransposon; Most recent common ancestor; Phylogenetic tree; Lineage (genetic); Evolutionary biology; Repertoire; Genome; Transposable element","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005536377,0.0001515336,0.00008819209,0.0003901372,0.0003286237,0.0002150749,0.0001313201,0.0002429434,0.00173298],"category_scores_gemma":[0.000101645,0.00009872648,0.0001530802,0.0002417843,0.0002861985,0.0001486206,0.0002471933,0.0002682682,0.0003292886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001655265,"about_ca_system_score_gemma":0.0001201991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0011439,"about_ca_topic_score_gemma":0.002429786,"domain_scores_codex":[0.9999652,0.00000278558,0.00000174919,0.00001540319,0.000007657407,0.000007247149],"domain_scores_gemma":[0.9999194,0.00001960758,0.00002361524,0.000008829951,0.000008915055,0.0000196007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002349933,0.00001000412,0.02125356,0.00005834191,0.0000146542,0.0005872468,0.0001591487,0.00007578144,0.9673555,0.0003644695,0.00006777093,0.009818555],"study_design_scores_gemma":[0.00004132046,0.000274251,0.9252914,0.00005162152,0.00007130084,0.008493335,0.0003607203,0.001130146,0.05052778,0.001062776,0.01267045,0.00002491336],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965661,0.0004006052,0.001037278,0.00002917955,0.000003686283,0.000003903407,0.0002476582,0.00002041994,0.001691276],"genre_scores_gemma":[0.9964697,0.0002048436,0.001522293,0.00004884962,0.000005822621,0.000008348971,0.0004252842,0.000008169385,0.001306629],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00173298,"threshold_uncertainty_score":0.005797386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08195811886310804,"score_gpt":0.3031235811479566,"score_spread":0.2211654622848486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}