{"id":"W2168219552","doi":"10.1128/iai.00645-08","title":"Prostaglandin E<sub>2</sub>Produced by<i>Entamoeba histolytica</i>Binds to EP4 Receptors and Stimulates Interleukin-8 Production in Human Colonic Cells","year":2008,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Ono Pharmaceutical; Canadian Association of Gastroenterology; University of Calgary","keywords":"Entamoeba histolytica; Biology; Proinflammatory cytokine; Receptor; Prostaglandin E; Chemokine; Interleukin 8; Prostaglandin E2; Mucin; Prostaglandin E2 receptor; Microbiology; Inflammation; Immunology; Endocrinology; Biochemistry; Agonist","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002224503,0.0002057618,0.0002852666,0.0003024917,0.0004475433,0.00002776971,0.00002493291,0.0001138039,0.00002613408],"category_scores_gemma":[0.0001053053,0.0001886051,0.0000436956,0.0003706664,0.0001518777,0.0001861803,0.00005245799,0.0003319192,0.00001694791],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000334565,"about_ca_system_score_gemma":0.00004400422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009715104,"about_ca_topic_score_gemma":0.000183479,"domain_scores_codex":[0.9989584,0.0001022702,0.0002440924,0.0003453745,0.0001157203,0.0002341144],"domain_scores_gemma":[0.9994128,0.00002898742,0.00007965483,0.000245116,0.00009514403,0.0001382742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002066283,0.0008613089,0.393113,0.0000653975,0.00007201019,0.00001135233,0.001198233,0.000007616802,0.5979106,0.00001316532,0.002902758,0.003637942],"study_design_scores_gemma":[0.002495245,0.001705061,0.3348848,0.0001273978,0.00007683813,0.000275489,0.000103302,0.00003179852,0.6564876,0.0000292253,0.003524092,0.0002591161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977976,0.0001087492,0.00001843248,0.0004513632,0.0004633153,0.0008380065,0.000004516852,0.000089012,0.0002289879],"genre_scores_gemma":[0.9986836,0.0003521952,0.00002439014,0.00009299877,0.00006158941,0.00007243715,0.00004110453,0.00002228628,0.0006494214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05857705,"threshold_uncertainty_score":0.7691092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0141331636445047,"score_gpt":0.2581786309421706,"score_spread":0.2440454672976659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}