{"id":"W2168268145","doi":"10.1096/fj.13-242446","title":"The chemokine CXC4 and CC2 receptors form homo‐ and heterooligomers that can engage their signaling G‐protein effectors and βarrestin","year":2014,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Chemokine receptor; G protein-coupled receptor; Cell biology; Receptor; Chemistry; CCR2; G protein; Arrestin; Chemokine; Signal transduction; Förster resonance energy transfer; Biophysics; Biology; Biochemistry; Fluorescence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002196032,0.0005992094,0.0002747712,0.0003295832,0.0002124269,0.0004023868,0.0002623716,0.0004432451,0.001851776],"category_scores_gemma":[0.0001999864,0.0002222758,0.0003664549,0.0002493205,0.0002993357,0.0003861993,0.0003680587,0.0004445122,0.0005434749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004739795,"about_ca_system_score_gemma":0.0002860389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008135069,"about_ca_topic_score_gemma":0.0009196475,"domain_scores_codex":[0.9997004,0.00006857661,0.00002007965,0.00005501748,0.0000754735,0.00008049067],"domain_scores_gemma":[0.9998764,0.00002051128,0.00004526195,0.00002014387,0.000014676,0.00002304284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006488675,0.00001856719,0.0003869899,0.00005114396,0.0000113051,0.00005804491,0.00001062594,0.00009883806,0.9973372,0.0003500009,0.00007868095,0.00153368],"study_design_scores_gemma":[0.00003463258,0.0002640676,0.01040937,0.00001132886,0.00003156389,0.0006675784,0.00004927853,0.001872423,0.9786386,0.0002930431,0.00771082,0.00001735136],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793901,0.004897921,0.01098808,0.0003261683,0.00005753233,0.0001053863,0.0006632602,0.0001745305,0.0033969],"genre_scores_gemma":[0.9828001,0.001914658,0.008807338,0.0002039571,0.00003207611,0.0001712931,0.001263874,0.00004223206,0.004764343],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001851776,"threshold_uncertainty_score":0.00619477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0129442822050176,"score_gpt":0.2199185168550398,"score_spread":0.2069742346500222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}