{"id":"W2168268145","doi":"10.1096/fj.13-242446","title":"The chemokine CXC4 and CC2 receptors form homo‐ and heterooligomers that can engage their signaling G‐protein effectors and βarrestin","year":2014,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Chemokine receptor; G protein-coupled receptor; Cell biology; Receptor; Chemistry; CCR2; G protein; Arrestin; Chemokine; Signal transduction; Förster resonance energy transfer; Biophysics; Biology; Biochemistry; Fluorescence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002346472,0.0002926273,0.000388391,0.00008293154,0.001112299,0.0002311343,0.0001425584,0.00009779727,0.00003826087],"category_scores_gemma":[0.0003075234,0.0001442953,0.0001001231,0.0001216002,0.0003407458,0.00008891198,0.0001034768,0.0009056128,0.00000102856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005631478,"about_ca_system_score_gemma":0.00003984572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005649936,"about_ca_topic_score_gemma":0.00002216888,"domain_scores_codex":[0.9984582,0.0002461768,0.0003074832,0.0002381993,0.0003066381,0.0004432682],"domain_scores_gemma":[0.9983942,0.0007691803,0.000210149,0.0002269671,0.00005787942,0.0003416417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003742157,0.00003939347,0.04002485,0.0001437737,0.0002489936,0.00002029681,0.003759374,0.000006871953,0.8407723,0.00008478417,0.0003820866,0.1141431],"study_design_scores_gemma":[0.00336861,0.0006226033,0.005108417,0.0007171658,0.0002187949,0.001748869,0.002572007,0.00119052,0.977589,0.0008630995,0.00561619,0.0003847076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945935,0.001972615,0.0001921505,0.002475175,0.0002218775,0.0003616293,0.000003743236,0.00003292016,0.0001464106],"genre_scores_gemma":[0.9979504,0.0006972637,0.0001735422,0.0002321273,0.0007049658,0.0000105971,0.000003818213,0.00004251017,0.0001848071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1368168,"threshold_uncertainty_score":0.855502,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0129442822050176,"score_gpt":0.2199185168550398,"score_spread":0.2069742346500222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}