{"id":"W2168302860","doi":"10.1016/j.psc.2014.09.001","title":"The Role of Nutrient-Based Epigenetic Changes in Buffering Against Stress, Aging, and Alzheimer’s Disease","year":2014,"lang":"en","type":"review","venue":"Psychiatric Clinics of North America","topic":"Diet and metabolism studies","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; McMaster University; Western University; Island Health; University of Toronto; Lawson Health Research Institute; McGill University; Christie (Canada); University of Victoria; University of British Columbia; NOSM University; Lakehead University","funders":"","keywords":"Epigenetics; Disease; Cognition; Alzheimer's disease; Brain aging; Neuroscience; Psychology; Cognitive decline; Cognitive aging; Bioinformatics; Medicine; Clinical psychology; Gerontology; Dementia; Biology; Genetics; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002971021,0.0004201577,0.002368422,0.0003262433,0.00007896766,0.000009780363,0.0002851707,0.00009095961,0.00000300365],"category_scores_gemma":[0.0003252182,0.0002854699,0.000479699,0.0007147851,0.0003471872,0.0000136987,0.0001284689,0.0003522036,0.000003386644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000169026,"about_ca_system_score_gemma":0.0003494581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005593303,"about_ca_topic_score_gemma":0.0001717874,"domain_scores_codex":[0.9975021,0.0001482855,0.001180207,0.0004533868,0.0003442562,0.0003717575],"domain_scores_gemma":[0.9968697,0.0008040217,0.001305032,0.000681854,0.0001116989,0.0002277148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005619546,0.0002511248,0.07574232,0.005954648,0.0002392711,0.000002065583,0.00003681536,0.000002975835,1.191601e-8,0.00001728348,0.00006007682,0.9176372],"study_design_scores_gemma":[0.0006384362,0.0002150776,0.01892037,0.003169625,0.003661274,2.305815e-7,0.00005538548,0.0000532691,1.823004e-7,0.00003245385,0.9730104,0.0002432508],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001432832,0.9965407,0.00001013745,0.000190089,0.0004867617,0.0009872288,0.000141761,0.00001814006,0.000192381],"genre_scores_gemma":[0.003623376,0.9953082,0.0003536203,0.0001084622,0.0003215226,0.0001112271,0.0001080194,0.00005391337,0.00001169202],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9729504,"threshold_uncertainty_score":0.9999598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02663083033937287,"score_gpt":0.3319934689150325,"score_spread":0.3053626385756597,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}