{"id":"W2168391996","doi":"10.1530/jme-12-0251","title":"Regulation of the osterix (Osx, Sp7) promoter by osterix and its inhibition by parathyroid hormone","year":2013,"lang":"en","type":"article","venue":"Journal of Molecular Endocrinology","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Parathyroid hormone; Transcription factor; Zinc finger; Chemistry; MAPK/ERK pathway; Zinc finger transcription factor; p38 mitogen-activated protein kinases; Messenger RNA; Cell biology; Phosphorylation; Molecular biology; Biology; Gene; Biochemistry; Calcium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000141413,0.0002925634,0.0002022465,0.0001353817,0.0001257864,0.0001930995,0.0001676256,0.0001588278,0.001306023],"category_scores_gemma":[0.0001357206,0.0001487383,0.0002672307,0.00009166263,0.0002662216,0.0001075561,0.0002661275,0.0004850696,0.0003022426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001890556,"about_ca_system_score_gemma":0.0001956989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004642254,"about_ca_topic_score_gemma":0.0005683318,"domain_scores_codex":[0.9997881,0.00003567343,0.00002090954,0.00004188664,0.00007299281,0.00004059951],"domain_scores_gemma":[0.9999001,0.00002335424,0.00003543008,0.000007293811,0.0000129817,0.00002079911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006083784,0.00001337634,0.00007750254,0.00001696625,0.000001459375,0.0000132467,0.000008196333,0.00002355101,0.9992076,0.00004771357,0.00001277094,0.0005167681],"study_design_scores_gemma":[0.00001443196,0.0001709296,0.002859784,0.000005201261,0.000006053839,0.0001075423,0.00002210771,0.000881478,0.9944824,0.00003656326,0.00141045,0.00000296295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921469,0.001889771,0.004118217,0.00009451694,0.00003143714,0.00003419069,0.000248322,0.00005286092,0.001383838],"genre_scores_gemma":[0.9912962,0.001129432,0.003754511,0.00004739206,0.00001536841,0.00008361477,0.0004942786,0.00002430007,0.003154982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001306023,"threshold_uncertainty_score":0.00436908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004237534582183003,"score_gpt":0.205745556399295,"score_spread":0.2015080218171119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}