{"id":"W2168445252","doi":"10.1186/2049-3002-1-9","title":"p53 promotes the expression of gluconeogenesis-related genes and enhances hepatic glucose production","year":2013,"lang":"en","type":"article","venue":"Cancer & Metabolism","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Azrieli Foundation; Weizmann Institute of Science; Flight Attendant Medical Research Institute","keywords":"Gluconeogenesis; Glycolysis; Pentose phosphate pathway; Transcriptome; Metabolic pathway; Carcinogenesis; Biology; Transcription factor; Biochemistry; Citric acid cycle; Phosphoenolpyruvate carboxykinase; Cell biology; Gene expression; Chemistry; Gene; Metabolism","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002021398,0.0002247542,0.0003079246,0.00004786095,0.000134586,0.00003145581,0.0002085049,0.0001403381,0.00009740306],"category_scores_gemma":[0.00008323053,0.0001527853,0.00009779526,0.0001551572,0.0002432057,0.00002212745,0.0001051524,0.0000902815,0.000006177905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006661448,"about_ca_system_score_gemma":0.0001023511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003645099,"about_ca_topic_score_gemma":0.00005997329,"domain_scores_codex":[0.9986503,0.0001178107,0.0003309847,0.0004510666,0.00018352,0.0002663813],"domain_scores_gemma":[0.9990074,0.00001341018,0.0002236459,0.0004547887,0.0002142289,0.00008651931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002987941,0.00003290326,0.0002764775,0.00004768646,0.0000583251,7.491415e-8,0.0002431002,0.00001960314,0.9343101,0.00003211853,0.0009052989,0.06404437],"study_design_scores_gemma":[0.0003613996,0.00003025402,0.008872882,0.00003506261,0.0001100205,0.000008366985,0.0001003286,0.00001557038,0.9089165,0.0002012868,0.081168,0.0001803518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.785327,0.2120105,0.00004142772,0.0002979736,0.001711193,0.0005103057,0.0000127497,0.00001442402,0.00007446705],"genre_scores_gemma":[0.9506154,0.04555814,0.000287871,0.0001027997,0.001771305,0.0004018393,0.00002111503,0.0000323795,0.001209128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1664523,"threshold_uncertainty_score":0.6230406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007626107610773075,"score_gpt":0.2366889287232319,"score_spread":0.2290628211124588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}