{"id":"W2168490581","doi":"10.1095/biolreprod.115.129718","title":"CYP26 Enzymes Are Necessary Within the Postnatal Seminiferous Epithelium for Normal Murine Spermatogenesis1","year":2015,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences","keywords":"Biology; Spermatogenesis; Sertoli cell; Germ cell; Seminiferous tubule; Epithelium; Germ line development; Retinoic acid; Gonocyte; Andrology; Internal medicine; Endocrinology; Cell biology; Blood–testis barrier; Genetics; Cell culture; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003379064,0.0006892788,0.0004585253,0.001117115,0.0004405903,0.0005039268,0.000393364,0.0005412349,0.004726117],"category_scores_gemma":[0.0002704059,0.0006095826,0.0004996913,0.0003031621,0.000430833,0.0002600163,0.0003358718,0.000792008,0.003120683],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000337232,"about_ca_system_score_gemma":0.0005628644,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009315721,"about_ca_topic_score_gemma":0.00171824,"domain_scores_codex":[0.9996082,0.00004440855,0.00004223546,0.00008958224,0.0001423759,0.00007326384],"domain_scores_gemma":[0.9988562,0.0000512137,0.0003452716,0.0001187855,0.0001727479,0.0004557281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002967643,0.00003930265,0.0008271067,0.00006930417,0.000008758607,0.0001796945,0.0000292545,0.00008691819,0.9954678,0.0003311479,0.000168783,0.002495095],"study_design_scores_gemma":[0.00007480955,0.0007787874,0.030568,0.00004008783,0.00005332776,0.001355209,0.00008061764,0.0006380997,0.9384671,0.0001585145,0.02776471,0.00002055221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9507761,0.01059126,0.02112378,0.0003874003,0.0002374514,0.00027783,0.00744771,0.001449659,0.007708846],"genre_scores_gemma":[0.9365062,0.005152159,0.01242067,0.0001020537,0.00007838722,0.0002320891,0.00794623,0.0005640668,0.03699829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004726117,"threshold_uncertainty_score":0.01581043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02044352973820346,"score_gpt":0.2642711809920587,"score_spread":0.2438276512538552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}