{"id":"W2168509294","doi":"10.1371/journal.pmed.1001300","title":"Multidrug Resistant Pulmonary Tuberculosis Treatment Regimens and Patient Outcomes: An Individual Patient Data Meta-analysis of 9,153 Patients","year":2012,"lang":"en","type":"review","venue":"PLoS Medicine","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":534,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Toronto","funders":"Canadian Institutes of Health Research; U.S. Public Health Service; Secretaría de Salud; Centers for Disease Control and Prevention; Otsuka Pharmaceutical; South African Medical Research Council; Wellcome Trust; Open Society Institute; National Institutes of Health; United States Agency for International Development; Global Fund to Fight AIDS, Tuberculosis and Malaria; World Health Organization; GlaxoSmithKline; Fogarty International Center; Pfizer; Bill and Melinda Gates Foundation; Eli Lilly and Company; National Institute of Allergy and Infectious Diseases; Medical Research Council; Howard Hughes Medical Institute","keywords":"Medicine; Ethionamide; Odds ratio; Tuberculosis; Internal medicine; Ofloxacin; Observational study; Meta-analysis; Extensively drug-resistant tuberculosis; Intensive care medicine; Mycobacterium tuberculosis; Antibiotics; Pathology; Ciprofloxacin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01901503,0.002033517,0.009461788,0.003028843,0.000541486,0.002375966,0.001698473,0.001661914,0.002523123],"category_scores_gemma":[0.02776885,0.001498661,0.04365619,0.004503873,0.0004685638,0.001253245,0.001490952,0.002142446,0.0003160666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001501765,"about_ca_system_score_gemma":0.001434211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004976153,"about_ca_topic_score_gemma":0.006803165,"domain_scores_codex":[0.9834217,0.01049273,0.002896466,0.001647756,0.001091877,0.0004493765],"domain_scores_gemma":[0.9774283,0.01608586,0.003431071,0.001651819,0.001039904,0.0003629498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.005906707,0.00003440246,0.02293595,0.01695449,0.9495429,0.0001304908,0.00004415565,0.0008189755,0.0001472922,0.00007251681,0.000514142,0.002897935],"study_design_scores_gemma":[0.001506563,0.0002985874,0.01202213,0.001306667,0.9831131,0.0001231781,0.00003351227,0.00049217,0.00009860462,0.0001737247,0.0008077771,0.00002406198],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1664487,0.8180053,0.004878934,0.0009004736,0.0005238751,0.0005912528,0.007273293,0.0001667494,0.001211463],"genre_scores_gemma":[0.9310555,0.06044582,0.003523696,0.0009182073,0.0001712233,0.0007078527,0.00272583,0.00007033828,0.000381475],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01901503,"threshold_uncertainty_score":0.1005623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3759251241039509,"score_gpt":0.4330672387976057,"score_spread":0.05714211469365477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}