{"id":"W2168591289","doi":"10.1074/jbc.m406853200","title":"Identifying Structural Features of Fibrillar Islet Amyloid Polypeptide Using Site-directed Spin Labeling","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Electron Spin Resonance Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Islet; Amyloid (mycology); Site-directed spin labeling; Chemistry; Computational biology; Biophysics; Biochemistry; Medicine; Biology; Pathology; Endocrinology; Diabetes mellitus","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001051295,0.0001870238,0.00008911576,0.0001835408,0.00008440803,0.0001602425,0.0001448267,0.0002486788,0.0003098758],"category_scores_gemma":[0.0001730501,0.0001101891,0.0001455548,0.00009042782,0.0001600224,0.0001256548,0.00009974876,0.0002741312,0.00008758264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007843939,"about_ca_system_score_gemma":0.00006693778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003104489,"about_ca_topic_score_gemma":0.0004302434,"domain_scores_codex":[0.9999615,0.000006712376,0.000002025577,0.00001136888,0.00001022888,0.000008098084],"domain_scores_gemma":[0.9998819,0.0000277466,0.00003725575,0.00001203814,0.0000222376,0.00001874218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001649706,0.00000407087,0.0002484171,0.000007954254,0.000001663757,0.00002154527,0.000008893817,0.00003197043,0.9990845,0.00001688314,0.000003788238,0.0005538569],"study_design_scores_gemma":[0.00001789666,0.0005381604,0.01712315,0.00001004534,0.00004197159,0.001007192,0.00008036715,0.004775899,0.975175,0.0001698707,0.001049903,0.00001058711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903995,0.0004878004,0.008455785,0.00002637945,0.00000607874,0.0000184922,0.00005232673,0.00002744944,0.0005262276],"genre_scores_gemma":[0.9821495,0.0007552851,0.01631334,0.00004432639,0.000006687321,0.00002049169,0.0002060599,0.00001567682,0.0004887151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003104489,"threshold_uncertainty_score":0.001036644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01990984931057615,"score_gpt":0.2968046972216074,"score_spread":0.2768948479110312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}