{"id":"W2168598580","doi":"10.1158/1940-6207.capr-10-0073","title":"Premalignant Breast Neoplasia: A Paradigm of Interlesional and Intralesional Molecular Heterogeneity and Its Biological and Clinical Ramifications","year":2010,"lang":"en","type":"review","venue":"Cancer Prevention Research","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Phenotype; Carcinogenesis; Breast cancer; Mammary gland; Disease; Biology; Pathology; Cancer research; Medicine; Cancer; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008051452,0.0002682891,0.000713473,0.000110403,0.0001382273,0.0000281648,0.0001782298,0.0005113962,0.00002474976],"category_scores_gemma":[0.0001390164,0.0002029604,0.0002038247,0.0001090368,0.0007194959,0.000006485689,0.0005417117,0.0004546519,0.000002146537],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002961592,"about_ca_system_score_gemma":0.000383636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001110052,"about_ca_topic_score_gemma":0.00008689007,"domain_scores_codex":[0.9974831,0.0006864846,0.0005439162,0.0007755804,0.0002278978,0.0002829676],"domain_scores_gemma":[0.9989772,0.0001669079,0.0002050468,0.0002788216,0.0001912894,0.0001807336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001437722,0.00033424,0.00594136,0.00229954,0.0007629227,0.000008592033,0.00001841115,1.35882e-7,0.001275921,0.0006573009,0.000109749,0.9884481],"study_design_scores_gemma":[0.004518475,0.002386197,0.1673661,0.01799123,0.00197819,0.00230134,0.00009802952,0.00004621141,0.00204489,0.001999363,0.7973946,0.001875385],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1015274,0.8970247,0.00005257634,0.0001676203,0.00007917089,0.0007354365,0.0003970263,0.000004201286,0.00001189388],"genre_scores_gemma":[0.03964822,0.9593698,0.0001567725,0.000007773692,0.0001541986,0.0003703221,0.0002198327,0.00002226149,0.0000508159],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9865727,"threshold_uncertainty_score":0.8276483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1598907099977788,"score_gpt":0.49070211473245,"score_spread":0.3308114047346712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}