{"id":"W2168614973","doi":"10.1002/embr.201338213","title":"S‐sulfhydration of MEK1 leads to PARP‐1 activation and DNA damage repair","year":2014,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":150,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lakehead University","funders":"Heart and Stroke Foundation of Canada","keywords":"Chemistry; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001352722,0.0003617742,0.0002461174,0.0001392314,0.0002310403,0.0002911882,0.0002761903,0.0002605951,0.003259444],"category_scores_gemma":[0.0001517649,0.0002297364,0.0003840297,0.0000983208,0.0002634942,0.0002423428,0.0003193652,0.0005259294,0.0004825047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000537728,"about_ca_system_score_gemma":0.0003757569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001496554,"about_ca_topic_score_gemma":0.002537225,"domain_scores_codex":[0.9998747,0.00001502154,0.000008242783,0.00002322733,0.00002690854,0.00005191953],"domain_scores_gemma":[0.9999112,0.00001527449,0.00002546855,0.00001659018,0.00001086604,0.0000205395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001089974,0.0001184551,0.0005714804,0.00005283498,0.00002549974,0.0001210133,0.00002456954,0.0004004549,0.993232,0.0004228516,0.0004519648,0.003488943],"study_design_scores_gemma":[0.00002264307,0.0001535536,0.002482767,0.000002235833,0.00000783022,0.0001434109,0.00002245233,0.0005545985,0.9952458,0.00009916851,0.001260558,0.000004903112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954748,0.0008364569,0.001258058,0.0002573627,0.00004779027,0.00001706055,0.0003125234,0.0001289174,0.001667068],"genre_scores_gemma":[0.9975399,0.0002145442,0.0003328638,0.00003128414,0.00000537016,0.000006452044,0.0002884594,0.00001348842,0.001567695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003259444,"threshold_uncertainty_score":0.01090395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008883723826812514,"score_gpt":0.2510820192156465,"score_spread":0.242198295388834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}