{"id":"W2168630726","doi":"10.1097/01.alc.0000153550.31168.1d","title":"CREB Gene Transcription Factors: Role in Molecular Mechanisms of Alcohol and Drug Addiction","year":2005,"lang":"en","type":"article","venue":"Alcoholism Clinical and Experimental Research","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Drug Abuse; National Institute on Alcohol Abuse and Alcoholism","keywords":"CREB; Addiction; Anxiety; Dopamine; Drug; Psychology; Transcription factor; Medicine; Psychiatry; Neuroscience; Gene; Chemistry; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000907653,0.0001782741,0.0002958318,0.0002336444,0.0001205267,0.00006150931,0.0002398073,0.0001370791,0.0001545324],"category_scores_gemma":[0.0001522988,0.0001624723,0.00009161172,0.0002955713,0.0006863954,0.0003831061,0.0001209185,0.0005625582,0.00002266148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003271983,"about_ca_system_score_gemma":0.00002698542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002320323,"about_ca_topic_score_gemma":0.000009265662,"domain_scores_codex":[0.9969256,0.0006253896,0.0006064098,0.0006992129,0.0006982014,0.0004451841],"domain_scores_gemma":[0.9990981,0.0003085508,0.00005844588,0.0002405164,0.0000373209,0.0002571085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001358178,0.0005437241,0.001877046,0.000005813508,0.000002947756,0.00001408702,0.0008209223,0.000002929312,0.9914392,0.0009874189,0.00002003297,0.004150089],"study_design_scores_gemma":[0.001450097,0.0002902679,0.008229991,0.00003027854,0.000005854109,0.00001009708,0.0003064941,0.0001364307,0.9883652,0.000765353,0.0002661077,0.000143871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981738,0.0004764134,0.00002910827,0.0003815777,0.0001015695,0.0005146959,0.00002021516,0.00002982069,0.0002728365],"genre_scores_gemma":[0.9987957,0.0003166311,0.0003872994,0.0002798859,0.00004655897,0.00006846335,0.000003150722,0.00002573669,0.00007655496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006352946,"threshold_uncertainty_score":0.6625428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1347145012608898,"score_gpt":0.4341415200779483,"score_spread":0.2994270188170585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}